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Large conserved domains of low DNA methylation maintained by Dnmt3a.
Jeong M, Sun D, Luo M, Huang Y, Challen GA, Rodriguez B, Zhang X, Chavez L, Wang H, Hannah R, Kim SB, Yang L, Ko M, Chen R, Göttgens B, Lee JS, Gunaratne P, Godley LA, Darlington GJ, Rao A, Li W, Goodell MA. Jeong M, et al. Among authors: chavez l. Nat Genet. 2014 Jan;46(1):17-23. doi: 10.1038/ng.2836. Epub 2013 Nov 24. Nat Genet. 2014. PMID: 24270360 Free PMC article.
DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer.
Grimm C, Chavez L, Vilardell M, Farrall AL, Tierling S, Böhm JW, Grote P, Lienhard M, Dietrich J, Timmermann B, Walter J, Schweiger MR, Lehrach H, Herwig R, Herrmann BG, Morkel M. Grimm C, et al. Among authors: chavez l. PLoS Genet. 2013;9(2):e1003250. doi: 10.1371/journal.pgen.1003250. Epub 2013 Feb 7. PLoS Genet. 2013. PMID: 23408899 Free PMC article.
Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility.
Seumois G, Chavez L, Gerasimova A, Lienhard M, Omran N, Kalinke L, Vedanayagam M, Ganesan AP, Chawla A, Djukanović R, Ansel KM, Peters B, Rao A, Vijayanand P. Seumois G, et al. Among authors: chavez l. Nat Immunol. 2014 Aug;15(8):777-88. doi: 10.1038/ni.2937. Epub 2014 Jul 6. Nat Immunol. 2014. PMID: 24997565 Free PMC article.
Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea.
Chavez L, Huang Y, Luong K, Agarwal S, Iyer LM, Pastor WA, Hench VK, Frazier-Bowers SA, Korol E, Liu S, Tahiliani M, Wang Y, Clark TA, Korlach J, Pukkila PJ, Aravind L, Rao A. Chavez L, et al. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):E5149-58. doi: 10.1073/pnas.1419513111. Epub 2014 Nov 18. Proc Natl Acad Sci U S A. 2014. PMID: 25406324 Free PMC article.
The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
Etchegaray JP, Chavez L, Huang Y, Ross KN, Choi J, Martinez-Pastor B, Walsh RM, Sommer CA, Lienhard M, Gladden A, Kugel S, Silberman DM, Ramaswamy S, Mostoslavsky G, Hochedlinger K, Goren A, Rao A, Mostoslavsky R. Etchegaray JP, et al. Among authors: chavez l. Nat Cell Biol. 2015 May;17(5):545-57. doi: 10.1038/ncb3147. Epub 2015 Apr 27. Nat Cell Biol. 2015. PMID: 25915124 Free PMC article.
Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis.
Kang J, Lienhard M, Pastor WA, Chawla A, Novotny M, Tsagaratou A, Lasken RS, Thompson EC, Surani MA, Koralov SB, Kalantry S, Chavez L, Rao A. Kang J, et al. Among authors: chavez l. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4236-45. doi: 10.1073/pnas.1510510112. Epub 2015 Jul 21. Proc Natl Acad Sci U S A. 2015. PMID: 26199412 Free PMC article.
342 results