Shannon K - Search Results

1

Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness.

Li Q, Bohin N, Wen T, Ng V, Magee J, Chen SC, Shannon K, Morrison SJ. Li Q, et al. Among authors: shannon k. Nature. 2013 Dec 5;504(7478):143-147. doi: 10.1038/nature12830. Epub 2013 Nov 27. Nature. 2013. PMID: 24284627 Free PMC article.

2

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder.

Braun BS, Tuveson DA, Kong N, Le DT, Kogan SC, Rozmus J, Le Beau MM, Jacks TE, Shannon KM. Braun BS, et al. Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):597-602. doi: 10.1073/pnas.0307203101. Epub 2003 Dec 29. Proc Natl Acad Sci U S A. 2004. PMID: 14699048 Free PMC article.

3

Germline KRAS mutations cause Noonan syndrome.

Schubbert S, Zenker M, Rowe SL, Böll S, Klein C, Bollag G, van der Burgt I, Musante L, Kalscheuer V, Wehner LE, Nguyen H, West B, Zhang KY, Sistermans E, Rauch A, Niemeyer CM, Shannon K, Kratz CP. Schubbert S, et al. Among authors: shannon k. Nat Genet. 2006 Mar;38(3):331-6. doi: 10.1038/ng1748. Epub 2006 Feb 12. Nat Genet. 2006. PMID: 16474405

4

MLL5 contributes to hematopoietic stem cell fitness and homeostasis.

Zhang Y, Wong J, Klinger M, Tran MT, Shannon KM, Killeen N. Zhang Y, et al. Blood. 2009 Feb 12;113(7):1455-63. doi: 10.1182/blood-2008-05-159905. Epub 2008 Sep 25. Blood. 2009. PMID: 18818388 Free PMC article.

5

Oncogenic Kras initiates leukemia in hematopoietic stem cells.

Sabnis AJ, Cheung LS, Dail M, Kang HC, Santaguida M, Hermiston ML, Passegué E, Shannon K, Braun BS. Sabnis AJ, et al. Among authors: shannon k. PLoS Biol. 2009 Mar 17;7(3):e59. doi: 10.1371/journal.pbio.1000059. PLoS Biol. 2009. PMID: 19296721 Free PMC article.

6

Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras.

Lauchle JO, Kim D, Le DT, Akagi K, Crone M, Krisman K, Warner K, Bonifas JM, Li Q, Coakley KM, Diaz-Flores E, Gorman M, Przybranowski S, Tran M, Kogan SC, Roose JP, Copeland NG, Jenkins NA, Parada L, Wolff L, Sebolt-Leopold J, Shannon K. Lauchle JO, et al. Among authors: shannon k. Nature. 2009 Sep 17;461(7262):411-4. doi: 10.1038/nature08279. Epub 2009 Sep 2. Nature. 2009. PMID: 19727076 Free PMC article.

7

Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents.

Dail M, Li Q, McDaniel A, Wong J, Akagi K, Huang B, Kang HC, Kogan SC, Shokat K, Wolff L, Braun BS, Shannon K. Dail M, et al. Among authors: shannon k. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5106-11. doi: 10.1073/pnas.1001064107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194733 Free PMC article.

8

Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.

Li Q, Haigis KM, McDaniel A, Harding-Theobald E, Kogan SC, Akagi K, Wong JC, Braun BS, Wolff L, Jacks T, Shannon K. Li Q, et al. Among authors: shannon k. Blood. 2011 Feb 10;117(6):2022-32. doi: 10.1182/blood-2010-04-280750. Epub 2010 Dec 16. Blood. 2011. PMID: 21163920 Free PMC article.

9

Oncogenic Ras scales the ALPS.

Shannon K, Li Q. Shannon K, et al. Blood. 2011 Mar 10;117(10):2747-8. doi: 10.1182/blood-2010-12-320721. Blood. 2011. PMID: 21393497 Free article. No abstract available.

10

Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras.

Xu J, Hedberg C, Dekker FJ, Li Q, Haigis KM, Hwang E, Waldmann H, Shannon K. Xu J, et al. Among authors: shannon k. Blood. 2012 Jan 26;119(4):1032-5. doi: 10.1182/blood-2011-06-358960. Epub 2011 Dec 5. Blood. 2012. PMID: 22144181 Free PMC article.

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