Crawford N - Search Results

1

Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer.

Riley JS, Hutchinson R, McArt DG, Crawford N, Holohan C, Paul I, Van Schaeybroeck S, Salto-Tellez M, Johnston PG, Fennell DA, Gately K, O'Byrne K, Cummins R, Kay E, Hamilton P, Stasik I, Longley DB. Riley JS, et al. Among authors: crawford n. Cell Death Dis. 2013 Dec 5;4(12):e951. doi: 10.1038/cddis.2013.481. Cell Death Dis. 2013. PMID: 24309938 Free PMC article.

2

Dynamical systems analysis of mitochondrial BAK activation kinetics predicts resistance to BH3 domains.

Grills C, Crawford N, Chacko A, Johnston PG, O'Rourke F, Fennell DA. Grills C, et al. Among authors: crawford n. PLoS One. 2008 Aug 22;3(8):e3038. doi: 10.1371/journal.pone.0003038. PLoS One. 2008. PMID: 18725943 Free PMC article.

3

Machine vision based stochastic analysis of cancer cell mitochondrial dysfunction induced by a BH3 domain.

Chacko AD, Crawford NT, Johnston PG, Fennell DA. Chacko AD, et al. Apoptosis. 2008 Nov;13(11):1386-93. doi: 10.1007/s10495-008-0262-1. Apoptosis. 2008. PMID: 18814032

4

Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing.

Wilson TR, Redmond KM, McLaughlin KM, Crawford N, Gately K, O'Byrne K, Le-Clorrenec C, Holohan C, Fennell DA, Johnston PG, Longley DB. Wilson TR, et al. Among authors: crawford n. Cell Death Differ. 2009 Oct;16(10):1352-61. doi: 10.1038/cdd.2009.76. Epub 2009 Jun 19. Cell Death Differ. 2009. PMID: 19543235

5

T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells.

Redmond KL, Crawford NT, Farmer H, D'Costa ZC, O'Brien GJ, Buckley NE, Kennedy RD, Johnston PG, Harkin DP, Mullan PB. Redmond KL, et al. Among authors: crawford nt. Oncogene. 2010 Jun 3;29(22):3252-62. doi: 10.1038/onc.2010.84. Epub 2010 Mar 29. Oncogene. 2010. PMID: 20348948

6

Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis.

Crawford N, Chacko AD, Savage KI, McCoy F, Redmond K, Longley DB, Fennell DA. Crawford N, et al. Apoptosis. 2011 Mar;16(3):311-20. doi: 10.1007/s10495-010-0561-1. Apoptosis. 2011. PMID: 21107700

7

The DeltaNp63 proteins are key allies of BRCA1 in the prevention of basal-like breast cancer.

Buckley NE, Conlon SJ, Jirstrom K, Kay EW, Crawford NT, O'Grady A, Sheehan K, Mc Dade SS, Wang CW, McCance DJ, Johnston PG, Kennedy RD, Harkin DP, Mullan PB. Buckley NE, et al. Cancer Res. 2011 Mar 1;71(5):1933-44. doi: 10.1158/0008-5472.CAN-10-2717. Cancer Res. 2011. PMID: 21363924

8

Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer.

Paul I, Chacko AD, Stasik I, Busacca S, Crawford N, McCoy F, McTavish N, Wilson B, Barr M, O'Byrne KJ, Longley DB, Fennell DA. Paul I, et al. Among authors: crawford n. Cell Death Dis. 2012 Dec 20;3(12):e449. doi: 10.1038/cddis.2012.186. Cell Death Dis. 2012. PMID: 23254292 Free PMC article.

9

SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma.

Crawford N, Stasik I, Holohan C, Majkut J, McGrath M, Johnston PG, Chessari G, Ward GA, Waugh DJ, Fennell DA, Longley DB. Crawford N, et al. Cell Death Dis. 2013 Jul 18;4(7):e733. doi: 10.1038/cddis.2013.258. Cell Death Dis. 2013. PMID: 23868066 Free PMC article.

10

Differential affinity of FLIP and procaspase 8 for FADD's DED binding surfaces regulates DISC assembly.

Majkut J, Sgobba M, Holohan C, Crawford N, Logan AE, Kerr E, Higgins CA, Redmond KL, Riley JS, Stasik I, Fennell DA, Van Schaeybroeck S, Haider S, Johnston PG, Haigh D, Longley DB. Majkut J, et al. Among authors: crawford n. Nat Commun. 2014 Feb 28;5:3350. doi: 10.1038/ncomms4350. Nat Commun. 2014. PMID: 24577104 Free PMC article.

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