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Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.
Tessneer KL, Pasula S, Cai X, Dong Y, McManus J, Liu X, Yu L, Hahn S, Chang B, Chen Y, Griffin C, Xia L, Adams RH, Chen H. Tessneer KL, et al. Among authors: yu l. Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):331-337. doi: 10.1161/ATVBAHA.113.302586. Epub 2013 Dec 5. Arterioscler Thromb Vasc Biol. 2014. PMID: 24311377 Free PMC article.
Motif mimetic of epsin perturbs tumor growth and metastasis.
Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H. Dong Y, et al. Among authors: yu l. J Clin Invest. 2015 Dec;125(12):4349-64. doi: 10.1172/JCI80349. Epub 2015 Nov 16. J Clin Invest. 2015. PMID: 26571402 Free PMC article.
Epsin-mediated degradation of IP3R1 fuels atherosclerosis.
Dong Y, Lee Y, Cui K, He M, Wang B, Bhattacharjee S, Zhu B, Yago T, Zhang K, Deng L, Ouyang K, Wen A, Cowan DB, Song K, Yu L, Brophy ML, Liu X, Wylie-Sears J, Wu H, Wong S, Cui G, Kawashima Y, Matsumoto H, Kodera Y, Wojcikiewicz RJH, Srivastava S, Bischoff J, Wang DZ, Ley K, Chen H. Dong Y, et al. Among authors: yu l. Nat Commun. 2020 Aug 7;11(1):3984. doi: 10.1038/s41467-020-17848-4. Nat Commun. 2020. PMID: 32770009 Free PMC article.
Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.
Song K, Cai X, Dong Y, Wu H, Wei Y, Shankavaram UT, Cui K, Lee Y, Zhu B, Bhattacharjee S, Wang B, Zhang K, Wen A, Wong S, Yu L, Xia L, Welm AL, Bielenberg DR, Camphausen KA, Kang Y, Chen H. Song K, et al. Among authors: yu l. J Clin Invest. 2021 Jan 4;131(1):e129374. doi: 10.1172/JCI129374. J Clin Invest. 2021. PMID: 32960814 Free PMC article.
Motif mimetic of epsin perturbs tumor growth and metastasis.
Dong Y, Wu H, Rahman HN, Liu Y, Pasula S, Tessneer KL, Cai X, Liu X, Chang B, McManus J, Hahn S, Dong J, Brophy ML, Yu L, Song K, Silasi-Mansat R, Saunders D, Njoku C, Song H, Mehta-D'Souza P, Towner R, Lupu F, McEver RP, Xia L, Boerboom D, Srinivasan RS, Chen H. Dong Y, et al. Among authors: yu l. J Clin Invest. 2016 Apr 1;126(4):1607. doi: 10.1172/JCI87344. Epub 2016 Mar 21. J Clin Invest. 2016. PMID: 26999611 Free PMC article. No abstract available.
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