Sharpe AH - Search Results

1

PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria.

Horne-Debets JM, Faleiro R, Karunarathne DS, Liu XQ, Lineburg KE, Poh CM, Grotenbreg GM, Hill GR, MacDonald KP, Good MF, Renia L, Ahmed R, Sharpe AH, Wykes MN. Horne-Debets JM, et al. Among authors: sharpe ah. Cell Rep. 2013 Dec 12;5(5):1204-13. doi: 10.1016/j.celrep.2013.11.002. Epub 2013 Dec 5. Cell Rep. 2013. PMID: 24316071 Free article.

2

Restoring function in exhausted CD8 T cells during chronic viral infection.

Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, Freeman GJ, Ahmed R. Barber DL, et al. Among authors: sharpe ah. Nature. 2006 Feb 9;439(7077):682-7. doi: 10.1038/nature04444. Epub 2005 Dec 28. Nature. 2006. PMID: 16382236

3

Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade.

Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH. Freeman GJ, et al. Among authors: sharpe ah. J Exp Med. 2006 Oct 2;203(10):2223-7. doi: 10.1084/jem.20061800. Epub 2006 Sep 25. J Exp Med. 2006. PMID: 17000870 Free PMC article. Review.

4

The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection.

Sharpe AH, Wherry EJ, Ahmed R, Freeman GJ. Sharpe AH, et al. Nat Immunol. 2007 Mar;8(3):239-45. doi: 10.1038/ni1443. Nat Immunol. 2007. PMID: 17304234 Review.

5

Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection.

Mueller SN, Matloubian M, Clemens DM, Sharpe AH, Freeman GJ, Gangappa S, Larsen CP, Ahmed R. Mueller SN, et al. Among authors: sharpe ah. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15430-5. doi: 10.1073/pnas.0702579104. Epub 2007 Sep 18. Proc Natl Acad Sci U S A. 2007. PMID: 17878315 Free PMC article.

6

Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection.

Ha SJ, Mueller SN, Wherry EJ, Barber DL, Aubert RD, Sharpe AH, Freeman GJ, Ahmed R. Ha SJ, et al. Among authors: sharpe ah. J Exp Med. 2008 Mar 17;205(3):543-55. doi: 10.1084/jem.20071949. Epub 2008 Mar 10. J Exp Med. 2008. PMID: 18332181 Free PMC article.

7

Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade.

Reynoso ED, Elpek KG, Francisco L, Bronson R, Bellemare-Pelletier A, Sharpe AH, Freeman GJ, Turley SJ. Reynoso ED, et al. Among authors: sharpe ah. J Immunol. 2009 Feb 15;182(4):2102-12. doi: 10.4049/jimmunol.0802769. J Immunol. 2009. PMID: 19201863 Free PMC article.

8

Role of PD-1 in regulating acute infections.

Brown KE, Freeman GJ, Wherry EJ, Sharpe AH. Brown KE, et al. Among authors: sharpe ah. Curr Opin Immunol. 2010 Jun;22(3):397-401. doi: 10.1016/j.coi.2010.03.007. Epub 2010 Apr 27. Curr Opin Immunol. 2010. PMID: 20427170 Free PMC article. Review.

9

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.

Mueller SN, Vanguri VK, Ha SJ, West EE, Keir ME, Glickman JN, Sharpe AH, Ahmed R. Mueller SN, et al. Among authors: sharpe ah. J Clin Invest. 2010 Jul;120(7):2508-15. doi: 10.1172/JCI40040. Epub 2010 Jun 14. J Clin Invest. 2010. PMID: 20551512 Free PMC article.

10

The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1.

Allen SJ, Hamrah P, Gate D, Mott KR, Mantopoulos D, Zheng L, Town T, Jones C, von Andrian UH, Freeman GJ, Sharpe AH, BenMohamed L, Ahmed R, Wechsler SL, Ghiasi H. Allen SJ, et al. Among authors: sharpe ah. J Virol. 2011 May;85(9):4184-97. doi: 10.1128/JVI.02290-10. Epub 2011 Feb 9. J Virol. 2011. PMID: 21307196 Free PMC article.

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