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The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Alemán JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR. Taniguchi CM, et al. Among authors: bronson rt. Cancer Res. 2010 Jul 1;70(13):5305-15. doi: 10.1158/0008-5472.CAN-09-3399. Epub 2010 Jun 8. Cancer Res. 2010. PMID: 20530665 Free PMC article.
PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer.
Ding L, Kim HJ, Wang Q, Kearns M, Jiang T, Ohlson CE, Li BB, Xie S, Liu JF, Stover EH, Howitt BE, Bronson RT, Lazo S, Roberts TM, Freeman GJ, Konstantinopoulos PA, Matulonis UA, Zhao JJ. Ding L, et al. Among authors: bronson rt. Cell Rep. 2018 Dec 11;25(11):2972-2980.e5. doi: 10.1016/j.celrep.2018.11.054. Cell Rep. 2018. PMID: 30540933 Free PMC article.
Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas.
Xie S, Ni J, McFaline-Figueroa JR, Wang Y, Bronson RT, Ligon KL, Wen PY, Roberts TM, Zhao JJ. Xie S, et al. Among authors: bronson rt. Cell Rep. 2020 Sep 29;32(13):108196. doi: 10.1016/j.celrep.2020.108196. Cell Rep. 2020. PMID: 32997991 Free PMC article.
Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma.
Davidson SM, Schmidt DR, Heyman JE, O'Brien JP, Liu AC, Israelsen WJ, Dayton TL, Sehgal R, Bronson RT, Freinkman E, Mak HH, Fanelli GN, Malstrom S, Bellinger G, Carracedo A, Pandolfi PP, Courtney KD, Jha A, DePinho RA, Horner JW, Thomas CJ, Cantley LC, Loda M, Vander Heiden MG. Davidson SM, et al. Among authors: bronson rt. Cancer Res. 2022 Jul 5;82(13):2403-2416. doi: 10.1158/0008-5472.CAN-21-2352. Cancer Res. 2022. PMID: 35584006 Free PMC article.
Chronic activation of wild-type epidermal growth factor receptor and loss of Cdkn2a cause mouse glioblastoma formation.
Acquaviva J, Jun HJ, Lessard J, Ruiz R, Zhu H, Donovan M, Woolfenden S, Boskovitz A, Raval A, Bronson RT, Pfannl R, Whittaker CA, Housman DE, Charest A. Acquaviva J, et al. Among authors: bronson rt. Cancer Res. 2011 Dec 1;71(23):7198-206. doi: 10.1158/0008-5472.CAN-11-1514. Epub 2011 Oct 10. Cancer Res. 2011. PMID: 21987724 Free PMC article.
548 results