Cantley LC - Search Results

1

A genetic mouse model of invasive endometrial cancer driven by concurrent loss of Pten and Lkb1 Is highly responsive to mTOR inhibition.

Cheng H, Liu P, Zhang F, Xu E, Symonds L, Ohlson CE, Bronson RT, Maira SM, Di Tomaso E, Li J, Myers AP, Cantley LC, Mills GB, Zhao JJ. Cheng H, et al. Among authors: cantley lc. Cancer Res. 2014 Jan 1;74(1):15-23. doi: 10.1158/0008-5472.CAN-13-0544. Epub 2013 Dec 9. Cancer Res. 2014. PMID: 24322983 Free PMC article.

2

Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha.

Fruman DA, Mauvais-Jarvis F, Pollard DA, Yballe CM, Brazil D, Bronson RT, Kahn CR, Cantley LC. Fruman DA, et al. Among authors: cantley lc. Nat Genet. 2000 Nov;26(3):379-82. doi: 10.1038/81715. Nat Genet. 2000. PMID: 11062485

3

The LKB1 tumor suppressor negatively regulates mTOR signaling.

Shaw RJ, Bardeesy N, Manning BD, Lopez L, Kosmatka M, DePinho RA, Cantley LC. Shaw RJ, et al. Among authors: cantley lc. Cancer Cell. 2004 Jul;6(1):91-9. doi: 10.1016/j.ccr.2004.06.007. Cancer Cell. 2004. PMID: 15261145 Free article.

4

Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase.

Luo J, Sobkiw CL, Logsdon NM, Watt JM, Signoretti S, O'Connell F, Shin E, Shim Y, Pao L, Neel BG, Depinho RA, Loda M, Cantley LC. Luo J, et al. Among authors: cantley lc. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10238-43. doi: 10.1073/pnas.0504378102. Epub 2005 Jul 8. Proc Natl Acad Sci U S A. 2005. PMID: 16006513 Free PMC article.

5

Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells.

Isakoff SJ, Engelman JA, Irie HY, Luo J, Brachmann SM, Pearline RV, Cantley LC, Brugge JS. Isakoff SJ, et al. Among authors: cantley lc. Cancer Res. 2005 Dec 1;65(23):10992-1000. doi: 10.1158/0008-5472.CAN-05-2612. Cancer Res. 2005. PMID: 16322248

6

Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.

Taniguchi CM, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley LC, Kahn CR. Taniguchi CM, et al. Among authors: cantley lc. Cell Metab. 2006 May;3(5):343-53. doi: 10.1016/j.cmet.2006.04.005. Cell Metab. 2006. PMID: 16679292 Free article.

7

The role of the ErbB family members in non-small cell lung cancers sensitive to epidermal growth factor receptor kinase inhibitors.

Engelman JA, Cantley LC. Engelman JA, et al. Among authors: cantley lc. Clin Cancer Res. 2006 Jul 15;12(14 Pt 2):4372s-4376s. doi: 10.1158/1078-0432.CCR-06-0795. Clin Cancer Res. 2006. PMID: 16857813 Review.

8

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.

Carracedo A, Ma L, Teruya-Feldstein J, Rojo F, Salmena L, Alimonti A, Egia A, Sasaki AT, Thomas G, Kozma SC, Papa A, Nardella C, Cantley LC, Baselga J, Pandolfi PP. Carracedo A, et al. Among authors: cantley lc. J Clin Invest. 2008 Sep;118(9):3065-74. doi: 10.1172/JCI34739. J Clin Invest. 2008. PMID: 18725988 Free PMC article.

9

Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation.

Zheng B, Jeong JH, Asara JM, Yuan YY, Granter SR, Chin L, Cantley LC. Zheng B, et al. Among authors: cantley lc. Mol Cell. 2009 Jan 30;33(2):237-47. doi: 10.1016/j.molcel.2008.12.026. Mol Cell. 2009. PMID: 19187764 Free PMC article.

10

Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling.

Gewinner C, Wang ZC, Richardson A, Teruya-Feldstein J, Etemadmoghadam D, Bowtell D, Barretina J, Lin WM, Rameh L, Salmena L, Pandolfi PP, Cantley LC. Gewinner C, et al. Among authors: cantley lc. Cancer Cell. 2009 Aug 4;16(2):115-25. doi: 10.1016/j.ccr.2009.06.006. Cancer Cell. 2009. PMID: 19647222 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

673 results

Search Page

Filters