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The costimulatory molecule CD70 is regulated by distinct molecular mechanisms and is associated with overall survival in diffuse large B-cell lymphoma.
Bertrand P, Maingonnat C, Penther D, Guney S, Ruminy P, Picquenot JM, Mareschal S, Alcantara M, Bouzelfen A, Dubois S, Figeac M, Bastard C, Tilly H, Jardin F. Bertrand P, et al. Among authors: bouzelfen a. Genes Chromosomes Cancer. 2013 Aug;52(8):764-74. doi: 10.1002/gcc.22072. Epub 2013 May 28. Genes Chromosomes Cancer. 2013. PMID: 23716461
HACE1 is a putative tumor suppressor gene in B-cell lymphomagenesis and is down-regulated by both deletion and epigenetic alterations.
Bouzelfen A, Alcantara M, Kora H, Picquenot JM, Bertrand P, Cornic M, Mareschal S, Bohers E, Maingonnat C, Ruminy P, Adriouch S, Boyer O, Dubois S, Bastard C, Tilly H, Latouche JB, Jardin F. Bouzelfen A, et al. Leuk Res. 2016 Jun;45:90-100. doi: 10.1016/j.leukres.2016.04.007. Epub 2016 Apr 11. Leuk Res. 2016. PMID: 27107267