Novellino E - Search Results

1

Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.

Salvati E, Zizza P, Rizzo A, Iachettini S, Cingolani C, D'Angelo C, Porru M, Randazzo A, Pagano B, Novellino E, Pisanu ME, Stoppacciaro A, Spinella F, Bagnato A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: novellino e. Nucleic Acids Res. 2014 Mar;42(5):2945-57. doi: 10.1093/nar/gkt1289. Epub 2013 Dec 11. Nucleic Acids Res. 2014. PMID: 24335081 Free PMC article.

2

Tandem application of virtual screening and NMR experiments in the discovery of brand new DNA quadruplex groove binders.

Cosconati S, Marinelli L, Trotta R, Virno A, Mayol L, Novellino E, Olson AJ, Randazzo A. Cosconati S, et al. Among authors: novellino e. J Am Chem Soc. 2009 Nov 18;131(45):16336-7. doi: 10.1021/ja9063662. J Am Chem Soc. 2009. PMID: 19856964

3

Structural and conformational requisites in DNA quadruplex groove binding: another piece to the puzzle.

Cosconati S, Marinelli L, Trotta R, Virno A, De Tito S, Romagnoli R, Pagano B, Limongelli V, Giancola C, Baraldi PG, Mayol L, Novellino E, Randazzo A. Cosconati S, et al. Among authors: novellino e. J Am Chem Soc. 2010 May 12;132(18):6425-33. doi: 10.1021/ja1003872. J Am Chem Soc. 2010. PMID: 20394365

4

Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)](4).

Pagano B, Fotticchia I, De Tito S, Mattia CA, Mayol L, Novellino E, Randazzo A, Giancola C. Pagano B, et al. Among authors: novellino e. J Nucleic Acids. 2010 May 30;2010:247137. doi: 10.4061/2010/247137. J Nucleic Acids. 2010. PMID: 20725616 Free PMC article.

5

The triazatruxene derivative azatrux binds to the parallel form of the human telomeric G-quadruplex under molecular crowding conditions: biophysical and molecular modeling studies.

Petraccone L, Fotticchia I, Cummaro A, Pagano B, Ginnari-Satriani L, Haider S, Randazzo A, Novellino E, Neidle S, Giancola C. Petraccone L, et al. Among authors: novellino e. Biochimie. 2011 Aug;93(8):1318-27. doi: 10.1016/j.biochi.2011.05.017. Epub 2011 May 30. Biochimie. 2011. PMID: 21641960

6

A more detailed picture of the interactions between virtual screening-derived hits and the DNA G-quadruplex: NMR, molecular modelling and ITC studies.

Trotta R, De Tito S, Lauri I, La Pietra V, Marinelli L, Cosconati S, Martino L, Conte MR, Mayol L, Novellino E, Randazzo A. Trotta R, et al. Among authors: novellino e. Biochimie. 2011 Aug;93(8):1280-7. doi: 10.1016/j.biochi.2011.05.021. Epub 2011 May 30. Biochimie. 2011. PMID: 21658428

7

State-of-the-art methodologies for the discovery and characterization of DNA G-quadruplex binders.

Pagano B, Cosconati S, Gabelica V, Petraccone L, De Tito S, Marinelli L, La Pietra V, di Leva FS, Lauri I, Trotta R, Novellino E, Giancola C, Randazzo A. Pagano B, et al. Among authors: novellino e. Curr Pharm Des. 2012;18(14):1880-99. doi: 10.2174/138161212799958332. Curr Pharm Des. 2012. PMID: 22376104 Free article. Review.

8

High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity.

Russo Krauss I, Merlino A, Randazzo A, Novellino E, Mazzarella L, Sica F. Russo Krauss I, et al. Among authors: novellino e. Nucleic Acids Res. 2012 Sep;40(16):8119-28. doi: 10.1093/nar/gks512. Epub 2012 Jun 4. Nucleic Acids Res. 2012. PMID: 22669903 Free PMC article.

9

Shooting for selective druglike G-quadruplex binders: evidence for telomeric DNA damage and tumor cell death.

Cosconati S, Rizzo A, Trotta R, Pagano B, Iachettini S, De Tito S, Lauri I, Fotticchia I, Giustiniano M, Marinelli L, Giancola C, Novellino E, Biroccio A, Randazzo A. Cosconati S, et al. Among authors: novellino e. J Med Chem. 2012 Nov 26;55(22):9785-92. doi: 10.1021/jm301019w. Epub 2012 Oct 18. J Med Chem. 2012. PMID: 23057850

10

The G-triplex DNA.

Limongelli V, De Tito S, Cerofolini L, Fragai M, Pagano B, Trotta R, Cosconati S, Marinelli L, Novellino E, Bertini I, Randazzo A, Luchinat C, Parrinello M. Limongelli V, et al. Among authors: novellino e. Angew Chem Int Ed Engl. 2013 Feb 18;52(8):2269-73. doi: 10.1002/anie.201206522. Epub 2013 Jan 17. Angew Chem Int Ed Engl. 2013. PMID: 23335456 No abstract available.

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