Frackelton AR Jr - Search Results

1

Coordinate regulation of estrogen-mediated fibronectin matrix assembly and epidermal growth factor receptor transactivation by the G protein-coupled receptor, GPR30.

Quinn JA, Graeber CT, Frackelton AR Jr, Kim M, Schwarzbauer JE, Filardo EJ. Quinn JA, et al. Among authors: frackelton ar jr. Mol Endocrinol. 2009 Jul;23(7):1052-64. doi: 10.1210/me.2008-0262. Epub 2009 Apr 2. Mol Endocrinol. 2009. PMID: 19342448 Free PMC article.

2

p66 Shc tumor levels show a strong prognostic correlation with disease outcome in stage IIA colon cancer.

Grossman SR, Lyle S, Resnick MB, Sabo E, Lis RT, Rosinha E, Liu Q, Hsieh CC, Bhat G, Frackelton AR Jr, Hafer LJ. Grossman SR, et al. Among authors: frackelton ar jr. Clin Cancer Res. 2007 Oct 1;13(19):5798-804. doi: 10.1158/1078-0432.CCR-07-0073. Clin Cancer Res. 2007. PMID: 17908971

3

p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy.

Frackelton AR Jr, Lu L, Davol PA, Bagdasaryan R, Hafer LJ, Sgroi DC. Frackelton AR Jr, et al. Breast Cancer Res. 2006;8(6):R73. doi: 10.1186/bcr1631. Breast Cancer Res. 2006. PMID: 17196107 Free PMC article.

4

Shc proteins are strong, independent prognostic markers for both node-negative and node-positive primary breast cancer.

Davol PA, Bagdasaryan R, Elfenbein GJ, Maizel AL, Frackelton AR Jr. Davol PA, et al. Among authors: frackelton ar jr. Cancer Res. 2003 Oct 15;63(20):6772-83. Cancer Res. 2003. PMID: 14583473

5

Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis.

Filardo EJ, Quinn JA, Frackelton AR Jr, Bland KI. Filardo EJ, et al. Among authors: frackelton ar jr. Mol Endocrinol. 2002 Jan;16(1):70-84. doi: 10.1210/mend.16.1.0758. Mol Endocrinol. 2002. PMID: 11773440

6

Src family tyrosine kinases participate in insulin-like growth factor I mitogenic signaling in 3T3-L1 cells.

Boney CM, Sekimoto H, Gruppuso PA, Frackelton AR Jr. Boney CM, et al. Among authors: frackelton ar jr. Cell Growth Differ. 2001 Jul;12(7):379-86. Cell Growth Differ. 2001. PMID: 11457735

7

Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF.

Filardo EJ, Quinn JA, Bland KI, Frackelton AR Jr. Filardo EJ, et al. Among authors: frackelton ar jr. Mol Endocrinol. 2000 Oct;14(10):1649-60. doi: 10.1210/mend.14.10.0532. Mol Endocrinol. 2000. PMID: 11043579

8

The critical role of Shc in insulin-like growth factor-I-mediated mitogenesis and differentiation in 3T3-L1 preadipocytes.

Boney CM, Gruppuso PA, Faris RA, Frackelton AR Jr. Boney CM, et al. Among authors: frackelton ar jr. Mol Endocrinol. 2000 Jun;14(6):805-13. doi: 10.1210/mend.14.6.0487. Mol Endocrinol. 2000. PMID: 10847583

9

Combining suramin and a chimeric toxin directed to basic fibroblast growth factor receptors increases therapeutic efficacy against human melanoma in an animal model.

Davol PA, Garza S, Frackelton AR Jr. Davol PA, et al. Among authors: frackelton ar jr. Cancer. 1999 Nov 1;86(9):1733-41. doi: 10.1002/(sici)1097-0142(19991101)86:9<1733::aid-cncr15>3.0.co;2-h. Cancer. 1999. PMID: 10547546

10

Wortmannin, a phosphoinositide 3-kinase inhibitor, selectively enhances cytotoxicity of receptor-directed-toxin chimeras in vitro and in vivo.

Davol PA, Bizuneh A, Frackelton AR Jr. Davol PA, et al. Among authors: frackelton ar jr. Anticancer Res. 1999 May-Jun;19(3A):1705-13. Anticancer Res. 1999. PMID: 10470104

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