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Aged mice are unable to mount an effective myeloid response to sepsis.
Nacionales DC, Gentile LF, Vanzant E, Lopez MC, Cuenca A, Cuenca AG, Ungaro R, Li Y, Baslanti TO, Bihorac A, Moore FA, Baker HV, Leeuwenburgh C, Moldawer LL, Efron PA. Nacionales DC, et al. Among authors: cuenca ag, cuenca a. J Immunol. 2014 Jan 15;192(2):612-22. doi: 10.4049/jimmunol.1302109. Epub 2013 Dec 13. J Immunol. 2014. PMID: 24337739 Free PMC article.
Sepsis induces early alterations in innate immunity that impact mortality to secondary infection.
Delano MJ, Thayer T, Gabrilovich S, Kelly-Scumpia KM, Winfield RD, Scumpia PO, Cuenca AG, Warner E, Wallet SM, Wallet MA, O'Malley KA, Ramphal R, Clare-Salzer M, Efron PA, Mathews CE, Moldawer LL. Delano MJ, et al. Among authors: cuenca ag. J Immunol. 2011 Jan 1;186(1):195-202. doi: 10.4049/jimmunol.1002104. Epub 2010 Nov 24. J Immunol. 2011. PMID: 21106855 Free PMC article.
Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling.
Delano MJ, Kelly-Scumpia KM, Thayer TC, Winfield RD, Scumpia PO, Cuenca AG, Harrington PB, O'Malley KA, Warner E, Gabrilovich S, Mathews CE, Laface D, Heyworth PG, Ramphal R, Strieter RM, Moldawer LL, Efron PA. Delano MJ, et al. Among authors: cuenca ag. J Immunol. 2011 Jul 15;187(2):911-8. doi: 10.4049/jimmunol.1100588. Epub 2011 Jun 20. J Immunol. 2011. PMID: 21690321 Free PMC article.
B cells enhance early innate immune responses during bacterial sepsis.
Kelly-Scumpia KM, Scumpia PO, Weinstein JS, Delano MJ, Cuenca AG, Nacionales DC, Wynn JL, Lee PY, Kumagai Y, Efron PA, Akira S, Wasserfall C, Atkinson MA, Moldawer LL. Kelly-Scumpia KM, et al. Among authors: cuenca ag. J Exp Med. 2011 Aug 1;208(8):1673-82. doi: 10.1084/jem.20101715. Epub 2011 Jul 11. J Exp Med. 2011. PMID: 21746813 Free PMC article.
A better understanding of why murine models of trauma do not recapitulate the human syndrome.
Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Baslanti TO, McKinley BA, Bihorac A, Cuschieri J, Maier RV, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA. Gentile LF, et al. Among authors: cuenca ag, cuenca a. Crit Care Med. 2014 Jun;42(6):1406-13. doi: 10.1097/CCM.0000000000000222. Crit Care Med. 2014. PMID: 24413577 Free PMC article.
Protective immunity and defects in the neonatal and elderly immune response to sepsis.
Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Cuenca AG, Ungaro R, Szpila BE, Larson S, Joseph A, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA. Gentile LF, et al. Among authors: cuenca ag, cuenca a. J Immunol. 2014 Apr 1;192(7):3156-65. doi: 10.4049/jimmunol.1301726. Epub 2014 Mar 3. J Immunol. 2014. PMID: 24591376 Free PMC article.
Host responses to sepsis vary in different low-lethality murine models.
Gentile LF, Nacionales DC, Lopez MC, Vanzant E, Cuenca A, Szpila BE, Cuenca AG, Joseph A, Moore FA, Leeuwenburgh C, Baker HV, Moldawer LL, Efron PA. Gentile LF, et al. Among authors: cuenca ag, cuenca a. PLoS One. 2014 May 1;9(5):e94404. doi: 10.1371/journal.pone.0094404. eCollection 2014. PLoS One. 2014. PMID: 24788351 Free PMC article.
Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia.
Cuenca AG, Cuenca AL, Winfield RD, Joiner DN, Gentile L, Delano MJ, Kelly-Scumpia KM, Scumpia PO, Matheny MK, Scarpace PJ, Vila L, Efron PA, LaFace DM, Moldawer LL. Cuenca AG, et al. Among authors: cuenca al. J Immunol. 2014 Jun 15;192(12):6111-9. doi: 10.4049/jimmunol.1302895. Epub 2014 May 14. J Immunol. 2014. PMID: 24829407 Free PMC article.
74 results