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Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice.
Schäfer M, Willrodt AH, Kurinna S, Link AS, Farwanah H, Geusau A, Gruber F, Sorg O, Huebner AJ, Roop DR, Sandhoff K, Saurat JH, Tschachler E, Schneider MR, Langbein L, Bloch W, Beer HD, Werner S. Schäfer M, et al. Among authors: bloch w. EMBO Mol Med. 2014 Apr;6(4):442-57. doi: 10.1002/emmm.201303281. Epub 2014 Feb 6. EMBO Mol Med. 2014. PMID: 24503019 Free PMC article.
Nrf2 links epidermal barrier function with antioxidant defense.
Schäfer M, Farwanah H, Willrodt AH, Huebner AJ, Sandhoff K, Roop D, Hohl D, Bloch W, Werner S. Schäfer M, et al. Among authors: bloch w. EMBO Mol Med. 2012 May;4(5):364-79. doi: 10.1002/emmm.201200219. Epub 2012 Mar 2. EMBO Mol Med. 2012. PMID: 22383093 Free PMC article.
Nrf3 promotes UV-induced keratinocyte apoptosis through suppression of cell adhesion.
Siegenthaler B, Defila C, Muzumdar S, Beer HD, Meyer M, Tanner S, Bloch W, Blank V, Schäfer M, Werner S. Siegenthaler B, et al. Among authors: bloch w. Cell Death Differ. 2018 Nov;25(10):1749-1765. doi: 10.1038/s41418-018-0074-y. Epub 2018 Feb 27. Cell Death Differ. 2018. PMID: 29487353 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34005085
Aldara activates TLR7-independent immune defence.
Walter A, Schäfer M, Cecconi V, Matter C, Urosevic-Maiwald M, Belloni B, Schönewolf N, Dummer R, Bloch W, Werner S, Beer HD, Knuth A, van den Broek M. Walter A, et al. Among authors: bloch w. Nat Commun. 2013;4:1560. doi: 10.1038/ncomms2566. Nat Commun. 2013. PMID: 23463003 Free article.
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