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Cancer: Inflammation lights the way to metastasis.
Coffelt SB, de Visser KE. Coffelt SB, et al. Nature. 2014 Mar 6;507(7490):48-9. doi: 10.1038/nature13062. Epub 2014 Feb 26. Nature. 2014. PMID: 24572360 No abstract available.
Neutrophils in cancer: neutral no more.
Coffelt SB, Wellenstein MD, de Visser KE. Coffelt SB, et al. Nat Rev Cancer. 2016 Jul;16(7):431-46. doi: 10.1038/nrc.2016.52. Epub 2016 Jun 10. Nat Rev Cancer. 2016. PMID: 27282249 Free article. Review.
Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages.
Kersten K, Coffelt SB, Hoogstraat M, Verstegen NJM, Vrijland K, Ciampricotti M, Doornebal CW, Hau CS, Wellenstein MD, Salvagno C, Doshi P, Lips EH, Wessels LFA, de Visser KE. Kersten K, et al. Among authors: coffelt sb. Oncoimmunology. 2017 Jun 19;6(8):e1334744. doi: 10.1080/2162402X.2017.1334744. eCollection 2017. Oncoimmunology. 2017. PMID: 28919995 Free PMC article.
Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response.
Salvagno C, Ciampricotti M, Tuit S, Hau CS, van Weverwijk A, Coffelt SB, Kersten K, Vrijland K, Kos K, Ulas T, Song JY, Ooi CH, Rüttinger D, Cassier PA, Jonkers J, Schultze JL, Ries CH, de Visser KE. Salvagno C, et al. Among authors: coffelt sb. Nat Cell Biol. 2019 Apr;21(4):511-521. doi: 10.1038/s41556-019-0298-1. Epub 2019 Mar 18. Nat Cell Biol. 2019. PMID: 30886344 Free PMC article.
Loss of p53 triggers WNT-dependent systemic inflammation to drive breast cancer metastasis.
Wellenstein MD, Coffelt SB, Duits DEM, van Miltenburg MH, Slagter M, de Rink I, Henneman L, Kas SM, Prekovic S, Hau CS, Vrijland K, Drenth AP, de Korte-Grimmerink R, Schut E, van der Heijden I, Zwart W, Wessels LFA, Schumacher TN, Jonkers J, de Visser KE. Wellenstein MD, et al. Among authors: coffelt sb. Nature. 2019 Aug;572(7770):538-542. doi: 10.1038/s41586-019-1450-6. Epub 2019 Jul 31. Nature. 2019. PMID: 31367040 Free PMC article.
69 results