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Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release.
Ilyinskii PO, Roy CJ, O'Neil CP, Browning EA, Pittet LA, Altreuter DH, Alexis F, Tonti E, Shi J, Basto PA, Iannacone M, Radovic-Moreno AF, Langer RS, Farokhzad OC, von Andrian UH, Johnston LP, Kishimoto TK. Ilyinskii PO, et al. Among authors: basto pa. Vaccine. 2014 May 19;32(24):2882-95. doi: 10.1016/j.vaccine.2014.02.027. Epub 2014 Mar 1. Vaccine. 2014. PMID: 24593999 Free PMC article.
HER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy.
Alexis F, Basto P, Levy-Nissenbaum E, Radovic-Moreno AF, Zhang L, Pridgen E, Wang AZ, Marein SL, Westerhof K, Molnar LK, Farokhzad OC. Alexis F, et al. ChemMedChem. 2008 Dec;3(12):1839-43. doi: 10.1002/cmdc.200800122. ChemMedChem. 2008. PMID: 19012296 Free PMC article.
Engineered nanomedicine for myeloma and bone microenvironment targeting.
Swami A, Reagan MR, Basto P, Mishima Y, Kamaly N, Glavey S, Zhang S, Moschetta M, Seevaratnam D, Zhang Y, Liu J, Memarzadeh M, Wu J, Manier S, Shi J, Bertrand N, Lu ZN, Nagano K, Baron R, Sacco A, Roccaro AM, Farokhzad OC, Ghobrial IM. Swami A, et al. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10287-92. doi: 10.1073/pnas.1401337111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982170 Free PMC article.
A vector-free microfluidic platform for intracellular delivery.
Sharei A, Zoldan J, Adamo A, Sim WY, Cho N, Jackson E, Mao S, Schneider S, Han MJ, Lytton-Jean A, Basto PA, Jhunjhunwala S, Lee J, Heller DA, Kang JW, Hartoularos GC, Kim KS, Anderson DG, Langer R, Jensen KF. Sharei A, et al. Among authors: basto pa. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2082-7. doi: 10.1073/pnas.1218705110. Epub 2013 Jan 22. Proc Natl Acad Sci U S A. 2013. PMID: 23341631 Free PMC article.
12 results