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PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation.
Bai P, Cantó C, Oudart H, Brunyánszki A, Cen Y, Thomas C, Yamamoto H, Huber A, Kiss B, Houtkooper RH, Schoonjans K, Schreiber V, Sauve AA, Menissier-de Murcia J, Auwerx J. Bai P, et al. Among authors: canto c. Cell Metab. 2011 Apr 6;13(4):461-468. doi: 10.1016/j.cmet.2011.03.004. Cell Metab. 2011. PMID: 21459330 Free PMC article.
The metabolic footprint of aging in mice.
Houtkooper RH, Argmann C, Houten SM, Cantó C, Jeninga EH, Andreux PA, Thomas C, Doenlen R, Schoonjans K, Auwerx J. Houtkooper RH, et al. Among authors: canto c. Sci Rep. 2011;1:134. doi: 10.1038/srep00134. Epub 2011 Oct 31. Sci Rep. 2011. PMID: 22355651 Free PMC article.
A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor.
Giroud-Gerbetant J, Joffraud M, Giner MP, Cercillieux A, Bartova S, Makarov MV, Zapata-Pérez R, Sánchez-García JL, Houtkooper RH, Migaud ME, Moco S, Canto C. Giroud-Gerbetant J, et al. Among authors: canto c. Mol Metab. 2019 Dec;30:192-202. doi: 10.1016/j.molmet.2019.09.013. Epub 2019 Oct 3. Mol Metab. 2019. PMID: 31767171 Free PMC article.
153 results