Channon KM - Search Results

1

GTP cyclohydrolase I prevents diabetic-impaired endothelial progenitor cells and wound healing by suppressing oxidative stress/thrombospondin-1.

Tie L, Chen LY, Chen DD, Xie HH, Channon KM, Chen AF. Tie L, et al. Among authors: channon km. Am J Physiol Endocrinol Metab. 2014 May 15;306(10):E1120-31. doi: 10.1152/ajpendo.00696.2013. Epub 2014 Mar 18. Am J Physiol Endocrinol Metab. 2014. PMID: 24644242 Free article.

2

GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.

Cai S, Alp NJ, McDonald D, Smith I, Kay J, Canevari L, Heales S, Channon KM. Cai S, et al. Among authors: channon km. Cardiovasc Res. 2002 Sep;55(4):838-49. doi: 10.1016/s0008-6363(02)00460-1. Cardiovasc Res. 2002. PMID: 12176133

3

Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.

Alp NJ, Mussa S, Khoo J, Cai S, Guzik T, Jefferson A, Goh N, Rockett KA, Channon KM. Alp NJ, et al. Among authors: channon km. J Clin Invest. 2003 Sep;112(5):725-35. doi: 10.1172/JCI17786. J Clin Invest. 2003. PMID: 12952921 Free PMC article.

4

Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.

Alp NJ, Channon KM. Alp NJ, et al. Among authors: channon km. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):413-20. doi: 10.1161/01.ATV.0000110785.96039.f6. Epub 2003 Dec 4. Arterioscler Thromb Vasc Biol. 2004. PMID: 14656731 Review.

5

Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.

Alp NJ, McAteer MA, Khoo J, Choudhury RP, Channon KM. Alp NJ, et al. Among authors: channon km. Arterioscler Thromb Vasc Biol. 2004 Mar;24(3):445-50. doi: 10.1161/01.ATV.0000115637.48689.77. Epub 2004 Jan 5. Arterioscler Thromb Vasc Biol. 2004. PMID: 14707037

6

Congenic mapping and genotyping of the tetrahydrobiopterin-deficient hph-1 mouse.

Khoo JP, Nicoli T, Alp NJ, Fullerton J, Flint J, Channon KM. Khoo JP, et al. Among authors: channon km. Mol Genet Metab. 2004 Jul;82(3):251-4. doi: 10.1016/j.ymgme.2004.04.006. Mol Genet Metab. 2004. PMID: 15234340

7

Reduced vascular NO bioavailability in diabetes increases platelet activation in vivo.

Schäfer A, Alp NJ, Cai S, Lygate CA, Neubauer S, Eigenthaler M, Bauersachs J, Channon KM. Schäfer A, et al. Among authors: channon km. Arterioscler Thromb Vasc Biol. 2004 Sep;24(9):1720-6. doi: 10.1161/01.ATV.0000138072.76902.dd. Epub 2004 Jul 8. Arterioscler Thromb Vasc Biol. 2004. PMID: 15242858

8

GTP cyclohydrolase I gene transfer reverses tetrahydrobiopterin deficiency and increases nitric oxide synthesis in endothelial cells and isolated vessels from diabetic rats.

Meininger CJ, Cai S, Parker JL, Channon KM, Kelly KA, Becker EJ, Wood MK, Wade LA, Wu G. Meininger CJ, et al. Among authors: channon km. FASEB J. 2004 Dec;18(15):1900-2. doi: 10.1096/fj.04-1702fje. Epub 2004 Oct 5. FASEB J. 2004. PMID: 15467010

9

Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.

Cai S, Khoo J, Channon KM. Cai S, et al. Among authors: channon km. Cardiovasc Res. 2005 Mar 1;65(4):823-31. doi: 10.1016/j.cardiores.2004.10.040. Cardiovasc Res. 2005. PMID: 15721862

10

Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension.

Khoo JP, Zhao L, Alp NJ, Bendall JK, Nicoli T, Rockett K, Wilkins MR, Channon KM. Khoo JP, et al. Among authors: channon km. Circulation. 2005 Apr 26;111(16):2126-33. doi: 10.1161/01.CIR.0000162470.26840.89. Epub 2005 Apr 11. Circulation. 2005. PMID: 15824200

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