Bhargavan B - Search Results

1

Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction.

Woollard SM, Bhargavan B, Yu F, Kanmogne GD. Woollard SM, et al. Among authors: bhargavan b. J Cereb Blood Flow Metab. 2014 Jun;34(6):1047-59. doi: 10.1038/jcbfm.2014.54. Epub 2014 Mar 26. J Cereb Blood Flow Metab. 2014. PMID: 24667918 Free PMC article. Clinical Trial.

2

Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication.

Bhargavan B, Woollard SM, Kanmogne GD. Bhargavan B, et al. Cell Signal. 2016 Feb;28(2):7-22. doi: 10.1016/j.cellsig.2015.11.005. Epub 2015 Nov 11. Cell Signal. 2016. PMID: 26569339 Free PMC article.

3

Differential Mechanisms of Inflammation and Endothelial Dysfunction by HIV-1 Subtype-B and Recombinant CRF02_AG Tat Proteins on Human Brain Microvascular Endothelial Cells: Implications for Viral Neuropathogenesis.

Bhargavan B, Kanmogne GD. Bhargavan B, et al. Mol Neurobiol. 2018 Feb;55(2):1352-1363. doi: 10.1007/s12035-017-0382-0. Epub 2017 Jan 27. Mol Neurobiol. 2018. PMID: 28127697 Free PMC article.

4

Toll-Like Receptor-3 Mediates HIV-1-Induced Interleukin-6 Expression in the Human Brain Endothelium via TAK1 and JNK Pathways: Implications for Viral Neuropathogenesis.

Bhargavan B, Kanmogne GD. Bhargavan B, et al. Mol Neurobiol. 2018 Jul;55(7):5976-5992. doi: 10.1007/s12035-017-0816-8. Epub 2017 Nov 11. Mol Neurobiol. 2018. PMID: 29128906 Free PMC article.

5

Epigenetics, N-myrystoyltransferase-1 and casein kinase-2-alpha modulates the increased replication of HIV-1 CRF02_AG, compared to subtype-B viruses.

Bhargavan B, Kanmogne GD. Bhargavan B, et al. Sci Rep. 2019 Jul 23;9(1):10689. doi: 10.1038/s41598-019-47069-9. Sci Rep. 2019. PMID: 31337802 Free PMC article.

6

CCR5 antagonist reduces HIV-induced amyloidogenesis, tau pathology, neurodegeneration, and blood-brain barrier alterations in HIV-infected hu-PBL-NSG mice.

Bhargavan B, Woollard SM, McMillan JE, Kanmogne GD. Bhargavan B, et al. Mol Neurodegener. 2021 Nov 22;16(1):78. doi: 10.1186/s13024-021-00500-0. Mol Neurodegener. 2021. PMID: 34809709 Free PMC article.

7

SARS-CoV-2 Spike Proteins and Cell-Cell Communication Inhibits TFPI and Induces Thrombogenic Factors in Human Lung Microvascular Endothelial Cells and Neutrophils: Implications for COVID-19 Coagulopathy Pathogenesis.

Bhargavan B, Kanmogne GD. Bhargavan B, et al. Int J Mol Sci. 2022 Sep 9;23(18):10436. doi: 10.3390/ijms231810436. Int J Mol Sci. 2022. PMID: 36142345 Free PMC article.

8

Data in support of NFκB and JNK pathways involvement in TLR3-mediated HIV-1 transactivation, expression of IL-6 and transcription factors associated with HIV-1 replication.

Bhargavan B, Woollard SM, Kanmogne GD. Bhargavan B, et al. Data Brief. 2015 Dec 17;6:345-51. doi: 10.1016/j.dib.2015.12.022. eCollection 2016 Mar. Data Brief. 2015. PMID: 26862581 Free PMC article.

9

Biodegradable polyanhydride-based nanomedicines for blood to brain drug delivery.

Brenza TM, Schlichtmann BW, Bhargavan B, Vela Ramirez JE, Nelson RD, Panthani MG, McMillan JM, Kalyanaraman B, Gendelman HE, Anantharam V, Kanthasamy AG, Mallapragada SK, Narasimhan B, Kanmogne GD. Brenza TM, et al. Among authors: bhargavan b. J Biomed Mater Res A. 2018 Nov;106(11):2881-2890. doi: 10.1002/jbm.a.36477. Epub 2018 Oct 26. J Biomed Mater Res A. 2018. PMID: 30369055 Free PMC article.

10

Creation of a long-acting nanoformulated dolutegravir.

Sillman B, Bade AN, Dash PK, Bhargavan B, Kocher T, Mathews S, Su H, Kanmogne GD, Poluektova LY, Gorantla S, McMillan J, Gautam N, Alnouti Y, Edagwa B, Gendelman HE. Sillman B, et al. Among authors: bhargavan b. Nat Commun. 2018 Feb 6;9(1):443. doi: 10.1038/s41467-018-02885-x. Nat Commun. 2018. PMID: 29402886 Free PMC article.

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