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The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response.
Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA. Puente BN, et al. Among authors: mahmoud ai. Cell. 2014 Apr 24;157(3):565-79. doi: 10.1016/j.cell.2014.03.032. Cell. 2014. PMID: 24766806 Free PMC article.
Transient regenerative potential of the neonatal mouse heart.
Porrello ER, Mahmoud AI, Simpson E, Hill JA, Richardson JA, Olson EN, Sadek HA. Porrello ER, et al. Among authors: mahmoud ai. Science. 2011 Feb 25;331(6020):1078-80. doi: 10.1126/science.1200708. Science. 2011. PMID: 21350179 Free PMC article.
The hypoxic epicardial and subepicardial microenvironment.
Kocabas F, Mahmoud AI, Sosic D, Porrello ER, Chen R, Garcia JA, DeBerardinis RJ, Sadek HA. Kocabas F, et al. Among authors: mahmoud ai. J Cardiovasc Transl Res. 2012 Oct;5(5):654-65. doi: 10.1007/s12265-012-9366-7. Epub 2012 May 8. J Cardiovasc Transl Res. 2012. PMID: 22566269
Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family.
Porrello ER, Mahmoud AI, Simpson E, Johnson BA, Grinsfelder D, Canseco D, Mammen PP, Rothermel BA, Olson EN, Sadek HA. Porrello ER, et al. Among authors: mahmoud ai. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):187-92. doi: 10.1073/pnas.1208863110. Epub 2012 Dec 17. Proc Natl Acad Sci U S A. 2013. PMID: 23248315 Free PMC article.
Meis1 regulates postnatal cardiomyocyte cell cycle arrest.
Mahmoud AI, Kocabas F, Muralidhar SA, Kimura W, Koura AS, Thet S, Porrello ER, Sadek HA. Mahmoud AI, et al. Nature. 2013 May 9;497(7448):249-253. doi: 10.1038/nature12054. Epub 2013 Apr 17. Nature. 2013. PMID: 23594737 Free PMC article.
Hippo pathway effector Yap promotes cardiac regeneration.
Xin M, Kim Y, Sutherland LB, Murakami M, Qi X, McAnally J, Porrello ER, Mahmoud AI, Tan W, Shelton JM, Richardson JA, Sadek HA, Bassel-Duby R, Olson EN. Xin M, et al. Among authors: mahmoud ai. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13839-44. doi: 10.1073/pnas.1313192110. Epub 2013 Aug 5. Proc Natl Acad Sci U S A. 2013. PMID: 23918388 Free PMC article.
Surgical models for cardiac regeneration in neonatal mice.
Mahmoud AI, Porrello ER, Kimura W, Olson EN, Sadek HA. Mahmoud AI, et al. Nat Protoc. 2014 Feb;9(2):305-11. doi: 10.1038/nprot.2014.021. Epub 2014 Jan 16. Nat Protoc. 2014. PMID: 24434799 Free PMC article.
Macrophages are required for neonatal heart regeneration.
Aurora AB, Porrello ER, Tan W, Mahmoud AI, Hill JA, Bassel-Duby R, Sadek HA, Olson EN. Aurora AB, et al. Among authors: mahmoud ai. J Clin Invest. 2014 Mar;124(3):1382-92. doi: 10.1172/JCI72181. Epub 2014 Feb 24. J Clin Invest. 2014. PMID: 24569380 Free PMC article.
40 results