Wu Z - Search Results

1

Identification of selective small molecule inhibitors of the nucleotide-binding oligomerization domain 1 (NOD1) signaling pathway.

Rickard DJ, Sehon CA, Kasparcova V, Kallal LA, Haile PA, Zeng X, Montoute MN, Poore DD, Li H, Wu Z, Eidam PM, Emery JG, Marquis RW, Gough PJ, Bertin J. Rickard DJ, et al. Among authors: wu z. PLoS One. 2014 May 7;9(5):e96737. doi: 10.1371/journal.pone.0096737. eCollection 2014. PLoS One. 2014. PMID: 24806487 Free PMC article.

2

Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway.

Rickard DJ, Sehon CA, Kasparcova V, Kallal LA, Zeng X, Montoute MN, Chordia T, Poore DD, Li H, Wu Z, Eidam PM, Haile PA, Yu J, Emery JG, Marquis RW, Gough PJ, Bertin J. Rickard DJ, et al. Among authors: wu z. PLoS One. 2013 Aug 1;8(8):e69619. doi: 10.1371/journal.pone.0069619. Print 2013. PLoS One. 2013. PMID: 23936340 Free PMC article.

3

High throughput screening identifies ATP-competitive inhibitors of the NLRP1 inflammasome.

Harris PA, Duraiswami C, Fisher DT, Fornwald J, Hoffman SJ, Hofmann G, Jiang M, Lehr R, McCormick PM, Nickels L, Schwartz B, Wu Z, Zhang G, Marquis RW, Bertin J, Gough PJ. Harris PA, et al. Among authors: wu z. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2739-43. doi: 10.1016/j.bmcl.2015.05.032. Epub 2015 May 19. Bioorg Med Chem Lett. 2015. PMID: 26022841

4

A High-Content Imaging Screen for Cellular Regulators of β-Catenin Protein Abundance.

Zeng X, Montoute M, Bee TW, Lin H, Kallal LA, Liu Y, Agarwal P, Wang D, Lu Q, Morrow D, Pope AJ, Wu Z. Zeng X, et al. Among authors: wu z. J Biomol Screen. 2016 Mar;21(3):260-8. doi: 10.1177/1087057115620169. Epub 2015 Dec 9. J Biomol Screen. 2016. PMID: 26656867

5

Development of phenotypic screening assays for γ-globin induction using primary human bone marrow day 7 erythroid progenitor cells.

Li H, Xie W, Gore ER, Montoute MN, Bee WT, Zappacosta F, Zeng X, Wu Z, Kallal L, Ames RS, Pope AJ, Benowitz A, Erickson-Miller CL. Li H, et al. Among authors: wu z. J Biomol Screen. 2013 Dec;18(10):1212-22. doi: 10.1177/1087057113499776. Epub 2013 Oct 25. J Biomol Screen. 2013. PMID: 24163393

6

A novel approach applying a chemical biology strategy in phenotypic screening reveals pathway-selective regulators of histone 3 K27 tri-methylation.

Liu Y, Platchek M, Kement B, Bee WT, Truong M, Zeng X, Hung S, Lin H, Morrow D, Kallal LA, Xie Q, Agarwal P, Pope AJ, Wu Z. Liu Y, et al. Among authors: wu z. Mol Biosyst. 2014 Feb;10(2):251-7. doi: 10.1039/c3mb70413k. Mol Biosyst. 2014. PMID: 24257700

7

Development of a High-Throughput Cul3-Keap1 Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET) Assay for Identifying Nrf2 Activators.

Poore DD, Hofmann G, Wolfe LA 3rd, Qi H, Jiang M, Fischer M, Wu Z, Sweitzer TD, Chakravorty S, Donovan B, Li H. Poore DD, et al. Among authors: wu z. SLAS Discov. 2019 Feb;24(2):175-189. doi: 10.1177/2472555218807698. Epub 2018 Nov 1. SLAS Discov. 2019. PMID: 30383469 Free article.

8

A Luciferase Reporter Gene System for High-Throughput Screening of γ-Globin Gene Activators.

Xie W, Silvers R, Ouellette M, Wu Z, Lu Q, Li H, Gallagher K, Johnson K, Montoute M. Xie W, et al. Among authors: wu z. Methods Mol Biol. 2016;1439:207-26. doi: 10.1007/978-1-4939-3673-1_14. Methods Mol Biol. 2016. PMID: 27316998

9

A hit deconstruction approach for the discovery of fetal hemoglobin inducers.

Benowitz AB, Eberl HC, Erickson-Miller CL, Gilmartin AG, Gore ER, Montoute MN, Wu Z. Benowitz AB, et al. Among authors: wu z. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3676-3680. doi: 10.1016/j.bmcl.2018.10.032. Epub 2018 Oct 22. Bioorg Med Chem Lett. 2018. PMID: 30554630

10

Screen for modulators of atonal homolog 1 gene expression using notch pathway-relevant gene transcription based cellular assays.

Zeng X, Kirkpatrick R, Hofmann G, Grillot D, Linhart V, Viviani F, Marino J Jr, Boyer J, Graham TL, Lu Q, Wu Z, Benowitz A, Cousins R. Zeng X, et al. Among authors: wu z. PLoS One. 2018 Dec 12;13(12):e0207140. doi: 10.1371/journal.pone.0207140. eCollection 2018. PLoS One. 2018. PMID: 30540745 Free PMC article.

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