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Anti-MAdCAM antibody (PF-00547659) for ulcerative colitis (TURANDOT): a phase 2, randomised, double-blind, placebo-controlled trial.
Vermeire S, Sandborn WJ, Danese S, Hébuterne X, Salzberg BA, Klopocka M, Tarabar D, Vanasek T, Greguš M, Hellstern PA, Kim JS, Sparrow MP, Gorelick KJ, Hinz M, Ahmad A, Pradhan V, Hassan-Zahraee M, Clare R, Cataldi F, Reinisch W. Vermeire S, et al. Among authors: cataldi f. Lancet. 2017 Jul 8;390(10090):135-144. doi: 10.1016/S0140-6736(17)30930-3. Epub 2017 May 17. Lancet. 2017. PMID: 28527704 Clinical Trial.
Effect of PF-00547659 on Central Nervous System Immune Surveillance and Circulating β7+ T Cells in Crohn's Disease: Report of the TOSCA Study.
D'Haens G, Vermeire S, Vogelsang H, Allez M, Desreumaux P, Van Gossum A, Sandborn WJ, Baumgart DC, Ransohoff RM, Comer GM, Ahmad A, Cataldi F, Cheng J, Clare R, Gorelick KJ, Kaminski A, Pradhan V, Rivers S, Sikpi MO, Zhang Y, Hassan-Zahraee M, Reinisch W, Stuve O. D'Haens G, et al. Among authors: cataldi f. J Crohns Colitis. 2018 Jan 24;12(2):188-196. doi: 10.1093/ecco-jcc/jjx128. J Crohns Colitis. 2018. PMID: 28961770 Free PMC article.
Phase II evaluation of anti-MAdCAM antibody PF-00547659 in the treatment of Crohn's disease: report of the OPERA study.
Sandborn WJ, Lee SD, Tarabar D, Louis E, Klopocka M, Klaus J, Reinisch W, Hébuterne X, Park DI, Schreiber S, Nayak S, Ahmad A, Banerjee A, Brown LS, Cataldi F, Gorelick KJ, Cheng JB, Hassan-Zahraee M, Clare R, D'Haens GR. Sandborn WJ, et al. Among authors: cataldi f. Gut. 2018 Oct;67(10):1824-1835. doi: 10.1136/gutjnl-2016-313457. Epub 2017 Oct 5. Gut. 2018. PMID: 28982740 Free PMC article. Clinical Trial.
Randomised trial and open-label extension study of an anti-interleukin-6 antibody in Crohn's disease (ANDANTE I and II).
Danese S, Vermeire S, Hellstern P, Panaccione R, Rogler G, Fraser G, Kohn A, Desreumaux P, Leong RW, Comer GM, Cataldi F, Banerjee A, Maguire MK, Li C, Rath N, Beebe J, Schreiber S. Danese S, et al. Among authors: cataldi f. Gut. 2019 Jan;68(1):40-48. doi: 10.1136/gutjnl-2017-314562. Epub 2017 Dec 15. Gut. 2019. PMID: 29247068 Free PMC article. Clinical Trial.
Targeting Endothelial Ligands: ICAM-1/alicaforsen, MAdCAM-1.
Reinisch W, Hung K, Hassan-Zahraee M, Cataldi F. Reinisch W, et al. Among authors: cataldi f. J Crohns Colitis. 2018 Aug 22;12(suppl_2):S669-S677. doi: 10.1093/ecco-jcc/jjy059. J Crohns Colitis. 2018. PMID: 29757363 Review.
Long-term Safety and Efficacy of the Anti-MAdCAM-1 Monoclonal Antibody Ontamalimab [SHP647] for the Treatment of Ulcerative Colitis: The Open-label Study TURANDOT II.
Reinisch W, Sandborn WJ, Danese S, Hébuterne X, Kłopocka M, Tarabar D, Vaňásek T, Greguš M, Hellstern PA, Kim JS, Sparrow MP, Gorelick KJ, Hoy M, Goetsch M, Bliss C, Gupta C, Cataldi F, Vermeire S. Reinisch W, et al. Among authors: cataldi f. J Crohns Colitis. 2021 Jun 22;15(6):938-949. doi: 10.1093/ecco-jcc/jjab023. J Crohns Colitis. 2021. PMID: 33599720 Free PMC article. Clinical Trial.
Challenges and Opportunities in IBD Clinical Trial Design.
Dubinsky MC, Collins R, Abreu MT; International Organization for the Study of Inflammatory Bowel Diseases (IOIBD). Dubinsky MC, et al. Gastroenterology. 2021 Aug;161(2):400-404. doi: 10.1053/j.gastro.2021.03.065. Epub 2021 Apr 20. Gastroenterology. 2021. PMID: 33864796 Free article. No abstract available.
39 results