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Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.
Liao Z, Gu L, Vergalli J, Mariani SA, De Dominici M, Lokareddy RK, Dagvadorj A, Purushottamachar P, McCue PA, Trabulsi E, Lallas CD, Gupta S, Ellsworth E, Blackmon S, Ertel A, Fortina P, Leiby B, Xia G, Rui H, Hoang DT, Gomella LG, Cingolani G, Njar V, Pattabiraman N, Calabretta B, Nevalainen MT. Liao Z, et al. Among authors: lokareddy rk. Mol Cancer Ther. 2015 Aug;14(8):1777-93. doi: 10.1158/1535-7163.MCT-14-0883. Epub 2015 May 29. Mol Cancer Ther. 2015. PMID: 26026053 Free PMC article.
The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD.
Sun J, Siroy A, Lokareddy RK, Speer A, Doornbos KS, Cingolani G, Niederweis M. Sun J, et al. Among authors: lokareddy rk. Nat Struct Mol Biol. 2015 Sep;22(9):672-8. doi: 10.1038/nsmb.3064. Epub 2015 Aug 3. Nat Struct Mol Biol. 2015. PMID: 26237511 Free PMC article.
A Greasy Aid to Capsid Assembly: Lessons from a Salty Virus.
Sankhala RS, Lokareddy RK, Cingolani G. Sankhala RS, et al. Among authors: lokareddy rk. Structure. 2015 Oct 6;23(10):1777-1779. doi: 10.1016/j.str.2015.09.002. Structure. 2015. PMID: 26445488 Free article.
37 results