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FcγRIIb on myeloid cells rather than on B cells protects from collagen-induced arthritis.
Yilmaz-Elis AS, Ramirez JM, Asmawidjaja P, van der Kaa J, Mus AM, Brem MD, Claassens JW, Breukel C, Brouwers C, Mangsbo SM, Boross P, Lubberts E, Verbeek JS. Yilmaz-Elis AS, et al. Among authors: verbeek js. J Immunol. 2014 Jun 15;192(12):5540-7. doi: 10.4049/jimmunol.1303272. Epub 2014 May 19. J Immunol. 2014. PMID: 24842758
Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII.
Boross P, van Lent PL, Martin-Ramirez J, van der Kaa J, Mulder MH, Claassens JW, van den Berg WB, Arandhara VL, Verbeek JS. Boross P, et al. Among authors: verbeek js. J Immunol. 2008 Apr 1;180(7):5083-91. doi: 10.4049/jimmunol.180.7.5083. J Immunol. 2008. PMID: 18354234
The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility.
Boross P, Arandhara VL, Martin-Ramirez J, Santiago-Raber ML, Carlucci F, Flierman R, van der Kaa J, Breukel C, Claassens JW, Camps M, Lubberts E, Salvatori D, Rastaldi MP, Ossendorp F, Daha MR, Cook HT, Izui S, Botto M, Verbeek JS. Boross P, et al. Among authors: verbeek js. J Immunol. 2011 Aug 1;187(3):1304-13. doi: 10.4049/jimmunol.1101194. Epub 2011 Jul 1. J Immunol. 2011. PMID: 21724994
A Restricted Role for FcγR in the Regulation of Adaptive Immunity.
Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS. Fransen MF, et al. Among authors: verbeek js. J Immunol. 2018 Apr 15;200(8):2615-2626. doi: 10.4049/jimmunol.1700429. Epub 2018 Mar 9. J Immunol. 2018. PMID: 29523656 Free PMC article.
Macrophages induce the inflammatory response in the pulmonary Arthus reaction through G alpha i2 activation that controls C5aR and Fc receptor cooperation.
Skokowa J, Ali SR, Felda O, Kumar V, Konrad S, Shushakova N, Schmidt RE, Piekorz RP, Nürnberg B, Spicher K, Birnbaumer L, Zwirner J, Claassens JW, Verbeek JS, van Rooijen N, Köhl J, Gessner JE. Skokowa J, et al. Among authors: verbeek js. J Immunol. 2005 Mar 1;174(5):3041-50. doi: 10.4049/jimmunol.174.5.3041. J Immunol. 2005. PMID: 15728518
134 results