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LCL124, a cationic analog of ceramide, selectively induces pancreatic cancer cell death by accumulating in mitochondria.
Beckham TH, Lu P, Jones EE, Marrison T, Lewis CS, Cheng JC, Ramshesh VK, Beeson G, Beeson CC, Drake RR, Bielawska A, Bielawski J, Szulc ZM, Ogretmen B, Norris JS, Liu X. Beckham TH, et al. Among authors: drake rr. J Pharmacol Exp Ther. 2013 Jan;344(1):167-78. doi: 10.1124/jpet.112.199216. Epub 2012 Oct 18. J Pharmacol Exp Ther. 2013. PMID: 23086228 Free PMC article.
Increased bisecting N-acetylglucosamine and decreased branched chain glycans of N-linked glycoproteins in expressed prostatic secretions associated with prostate cancer progression.
Nyalwidhe JO, Betesh LR, Powers TW, Jones EE, White KY, Burch TC, Brooks J, Watson MT, Lance RS, Troyer DA, Semmes OJ, Mehta A, Drake RR. Nyalwidhe JO, et al. Among authors: drake rr. Proteomics Clin Appl. 2013 Oct;7(9-10):677-89. doi: 10.1002/prca.201200134. Epub 2013 Sep 13. Proteomics Clin Appl. 2013. PMID: 23775902 Free PMC article.
212 results