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SHP2 regulates osteoclastogenesis by promoting preosteoclast fusion.
Zhou Y, Mohan A, Moore DC, Lin L, Zhou FL, Cao J, Wu Q, Qin YX, Reginato AM, Ehrlich MG, Yang W. Zhou Y, et al. Among authors: yang w. FASEB J. 2015 May;29(5):1635-45. doi: 10.1096/fj.14-260844. Epub 2015 Jan 15. FASEB J. 2015. PMID: 25593124 Free PMC article.
A ERK/RSK-mediated negative feedback loop regulates M-CSF-evoked PI3K/AKT activation in macrophages.
Wang L, Iorio C, Yan K, Yang H, Takeshita S, Kang S, Neel BG, Yang W. Wang L, et al. Among authors: yang w, yang h. FASEB J. 2018 Feb;32(2):875-887. doi: 10.1096/fj.201700672RR. Epub 2018 Jan 4. FASEB J. 2018. PMID: 29046360 Free PMC article.
Furthermore, this increase in PI3K/AKT activation enables BMM survival in the setting of SHP2 deficiency.-Wang, L., Iorio, C., Yan, K., Yang, H., Takeshita, S., Kang, S., Neel, B.G., Yang, W. An ERK/RSK-mediated negative feedback loop regulates M-CSF-evoked P …
Furthermore, this increase in PI3K/AKT activation enables BMM survival in the setting of SHP2 deficiency.-Wang, L., Iorio, C., Yan, K., Y …
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