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Male fertility defect associated with disrupted BRCA1-PALB2 interaction in mice.
Simhadri S, Peterson S, Patel DS, Huo Y, Cai H, Bowman-Colin C, Miller S, Ludwig T, Ganesan S, Bhaumik M, Bunting SF, Jasin M, Xia B. Simhadri S, et al. Among authors: cai h. J Biol Chem. 2014 Aug 29;289(35):24617-29. doi: 10.1074/jbc.M114.566141. Epub 2014 Jul 11. J Biol Chem. 2014. PMID: 25016020 Free PMC article.
PALB2 interacts with KEAP1 to promote NRF2 nuclear accumulation and function.
Ma J, Cai H, Wu T, Sobhian B, Huo Y, Alcivar A, Mehta M, Cheung KL, Ganesan S, Kong AN, Zhang DD, Xia B. Ma J, et al. Among authors: cai h. Mol Cell Biol. 2012 Apr;32(8):1506-17. doi: 10.1128/MCB.06271-11. Epub 2012 Feb 13. Mol Cell Biol. 2012. PMID: 22331464 Free PMC article.
Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Bowman-Colin C, Xia B, Bunting S, Klijn C, Drost R, Bouwman P, Fineman L, Chen X, Culhane AC, Cai H, Rodig SJ, Bronson RT, Jonkers J, Nussenzweig A, Kanellopoulou C, Livingston DM. Bowman-Colin C, et al. Among authors: cai h. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8632-7. doi: 10.1073/pnas.1305362110. Epub 2013 May 8. Proc Natl Acad Sci U S A. 2013. PMID: 23657012 Free PMC article.
PALB2 links BRCA1 and BRCA2 in the DNA-damage response.
Zhang F, Ma J, Wu J, Ye L, Cai H, Xia B, Yu X. Zhang F, et al. Among authors: cai h. Curr Biol. 2009 Mar 24;19(6):524-9. doi: 10.1016/j.cub.2009.02.018. Epub 2009 Mar 5. Curr Biol. 2009. PMID: 19268590 Free PMC article.
8,724 results