Der CJ - Search Results

1

Inhibitors of the ERK mitogen-activated protein kinase cascade for targeting RAS mutant cancers.

Gentry L, Samatar AA, Der CJ. Gentry L, et al. Among authors: der cj. Enzymes. 2013;34 Pt. B:67-106. doi: 10.1016/B978-0-12-420146-0.00004-4. Epub 2013 Nov 7. Enzymes. 2013. PMID: 25034101 Review.

2

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation.

Khosravi-Far R, Solski PA, Clark GJ, Kinch MS, Der CJ. Khosravi-Far R, et al. Among authors: der cj. Mol Cell Biol. 1995 Nov;15(11):6443-53. doi: 10.1128/MCB.15.11.6443. Mol Cell Biol. 1995. PMID: 7565796 Free PMC article.

3

Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras.

Khosravi-Far R, Chrzanowska-Wodnicka M, Solski PA, Eva A, Burridge K, Der CJ. Khosravi-Far R, et al. Among authors: der cj. Mol Cell Biol. 1994 Oct;14(10):6848-57. doi: 10.1128/mcb.14.10.6848-6857.1994. Mol Cell Biol. 1994. PMID: 7935402 Free PMC article.

4

Differential activation of the Ras/extracellular-signal-regulated protein kinase pathway is responsible for the biological consequences induced by the Axl receptor tyrosine kinase.

Fridell YW, Jin Y, Quilliam LA, Burchert A, McCloskey P, Spizz G, Varnum B, Der C, Liu ET. Fridell YW, et al. Mol Cell Biol. 1996 Jan;16(1):135-45. doi: 10.1128/MCB.16.1.135. Mol Cell Biol. 1996. PMID: 8524290 Free PMC article.

5

Peptides containing a consensus Ras binding sequence from Raf-1 and theGTPase activating protein NF1 inhibit Ras function.

Clark GJ, Drugan JK, Terrell RS, Bradham C, Der CJ, Bell RM, Campbell S. Clark GJ, et al. Among authors: der cj. Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1577-81. doi: 10.1073/pnas.93.4.1577. Proc Natl Acad Sci U S A. 1996. PMID: 8643674 Free PMC article.

6

Integrin-mediated activation of MEK and mitogen-activated protein kinase is independent of Ras [corrected].

Chen Q, Lin TH, Der CJ, Juliano RL. Chen Q, et al. Among authors: der cj. J Biol Chem. 1996 Jul 26;271(30):18122-7. doi: 10.1074/jbc.271.30.18122. J Biol Chem. 1996. PMID: 8663436 Free article.

7

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation.

Khosravi-Far R, White MA, Westwick JK, Solski PA, Chrzanowska-Wodnicka M, Van Aelst L, Wigler MH, Der CJ. Khosravi-Far R, et al. Among authors: der cj. Mol Cell Biol. 1996 Jul;16(7):3923-33. doi: 10.1128/MCB.16.7.3923. Mol Cell Biol. 1996. PMID: 8668210 Free PMC article.

8

p120 GAP modulates Ras activation of Jun kinases and transformation.

Clark GJ, Westwick JK, Der CJ. Clark GJ, et al. Among authors: der cj. J Biol Chem. 1997 Jan 17;272(3):1677-81. doi: 10.1074/jbc.272.3.1677. J Biol Chem. 1997. PMID: 8999845 Free article.

9

Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

Cox AD, Der CJ. Cox AD, et al. Among authors: der cj. Biochim Biophys Acta. 1997 Aug 8;1333(1):F51-71. doi: 10.1016/s0304-419x(97)00011-5. Biochim Biophys Acta. 1997. PMID: 9294018 Review. No abstract available.

10

Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade.

Oldham SM, Cox AD, Reynolds ER, Sizemore NS, Coffey RJ Jr, Der CJ. Oldham SM, et al. Among authors: der cj. Oncogene. 1998 May;16(20):2565-73. doi: 10.1038/sj.onc.1201784. Oncogene. 1998. PMID: 9632133

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