Hunter RW - Search Results

1

Mechanism of action of compound-13: an α1-selective small molecule activator of AMPK.

Hunter RW, Foretz M, Bultot L, Fullerton MD, Deak M, Ross FA, Hawley SA, Shpiro N, Viollet B, Barron D, Kemp BE, Steinberg GR, Hardie DG, Sakamoto K. Hunter RW, et al. Chem Biol. 2014 Jul 17;21(7):866-79. doi: 10.1016/j.chembiol.2014.05.014. Chem Biol. 2014. PMID: 25036776 Free PMC article.

2

Cyclin Y phosphorylation- and 14-3-3-binding-dependent activation of PCTAIRE-1/CDK16.

Shehata SN, Deak M, Morrice NA, Ohta E, Hunter RW, Kalscheuer VM, Sakamoto K. Shehata SN, et al. Among authors: hunter rw. Biochem J. 2015 Aug 1;469(3):409-20. doi: 10.1042/BJ20150486. Epub 2015 Jun 11. Biochem J. 2015. PMID: 26205494 Free PMC article.

3

Molecular mechanism by which AMP-activated protein kinase activation promotes glycogen accumulation in muscle.

Hunter RW, Treebak JT, Wojtaszewski JF, Sakamoto K. Hunter RW, et al. Diabetes. 2011 Mar;60(3):766-74. doi: 10.2337/db10-1148. Epub 2011 Jan 31. Diabetes. 2011. PMID: 21282366 Free PMC article.

4

Structural basis for the recruitment of glycogen synthase by glycogenin.

Zeqiraj E, Tang X, Hunter RW, García-Rocha M, Judd A, Deak M, von Wilamowitz-Moellendorff A, Kurinov I, Guinovart JJ, Tyers M, Sakamoto K, Sicheri F. Zeqiraj E, et al. Among authors: hunter rw. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2831-40. doi: 10.1073/pnas.1402926111. Epub 2014 Jun 30. Proc Natl Acad Sci U S A. 2014. PMID: 24982189 Free PMC article.

5

Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase.

Shehata SN, Hunter RW, Ohta E, Peggie MW, Lou HJ, Sicheri F, Zeqiraj E, Turk BE, Sakamoto K. Shehata SN, et al. Among authors: hunter rw. Cell Signal. 2012 Nov;24(11):2085-94. doi: 10.1016/j.cellsig.2012.06.018. Epub 2012 Jul 11. Cell Signal. 2012. PMID: 22796189 Free PMC article.

6

Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis.

von Wilamowitz-Moellendorff A, Hunter RW, García-Rocha M, Kang L, López-Soldado I, Lantier L, Patel K, Peggie MW, Martínez-Pons C, Voss M, Calbó J, Cohen PT, Wasserman DH, Guinovart JJ, Sakamoto K. von Wilamowitz-Moellendorff A, et al. Among authors: hunter rw. Diabetes. 2013 Dec;62(12):4070-82. doi: 10.2337/db13-0880. Epub 2013 Aug 29. Diabetes. 2013. PMID: 23990365 Free PMC article.

7

Mutation in the γ2-subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage.

Kim M, Hunter RW, Garcia-Menendez L, Gong G, Yang YY, Kolwicz SC Jr, Xu J, Sakamoto K, Wang W, Tian R. Kim M, et al. Among authors: hunter rw. Circ Res. 2014 Mar 14;114(6):966-75. doi: 10.1161/CIRCRESAHA.114.302364. Epub 2014 Feb 6. Circ Res. 2014. PMID: 24503893 Free PMC article.

8

Expression and purification of functional human glycogen synthase-1:glycogenin-1 complex in insect cells.

Hunter RW, Zeqiraj E, Morrice N, Sicheri F, Sakamoto K. Hunter RW, et al. Protein Expr Purif. 2015 Apr;108:23-29. doi: 10.1016/j.pep.2014.12.007. Epub 2014 Dec 17. Protein Expr Purif. 2015. PMID: 25527037 Free PMC article.

9

Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase.

Hunter RW, Hughey CC, Lantier L, Sundelin EI, Peggie M, Zeqiraj E, Sicheri F, Jessen N, Wasserman DH, Sakamoto K. Hunter RW, et al. Nat Med. 2018 Sep;24(9):1395-1406. doi: 10.1038/s41591-018-0159-7. Epub 2018 Aug 27. Nat Med. 2018. PMID: 30150719 Free PMC article.

10

Allosteric regulation of glycogen synthase controls glycogen synthesis in muscle.

Bouskila M, Hunter RW, Ibrahim AF, Delattre L, Peggie M, van Diepen JA, Voshol PJ, Jensen J, Sakamoto K. Bouskila M, et al. Among authors: hunter rw. Cell Metab. 2010 Nov 3;12(5):456-66. doi: 10.1016/j.cmet.2010.10.006. Cell Metab. 2010. PMID: 21035757 Free article.

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