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13 results

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Page 1
Safety, pharmacokinetic, and clinical activity profiles of ramucirumab in combination with three platinum/fluoropyrimidine doublets in Japanese patients with chemotherapy-naïve metastatic gastric/gastroesophageal junction cancer.
Shitara K, Kadowaki S, Nishina T, Sakai D, Yoshikawa R, Piao Y, Ozeki A, Inoue K, Gritli I, Muro K. Shitara K, et al. Among authors: gritli i. Gastric Cancer. 2018 Jan;21(1):106-113. doi: 10.1007/s10120-017-0745-2. Epub 2017 Jun 30. Gastric Cancer. 2018. PMID: 28667466 Clinical Trial.
Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA.
Zuckerman JE, Gritli I, Tolcher A, Heidel JD, Lim D, Morgan R, Chmielowski B, Ribas A, Davis ME, Yen Y. Zuckerman JE, et al. Among authors: gritli i. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11449-54. doi: 10.1073/pnas.1411393111. Epub 2014 Jul 21. Proc Natl Acad Sci U S A. 2014. PMID: 25049380 Free PMC article. Clinical Trial.
Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking.
Sato A, Nishida C, Sato-Kusubata K, Ishihara M, Tashiro Y, Gritli I, Shimazu H, Munakata S, Yagita H, Okumura K, Tsuda Y, Okada Y, Tojo A, Nakauchi H, Takahashi S, Heissig B, Hattori K. Sato A, et al. Among authors: gritli i. Leukemia. 2015 Jan;29(1):145-56. doi: 10.1038/leu.2014.151. Epub 2014 May 5. Leukemia. 2015. PMID: 24791857
Inhibition of PAI-1 induces neutrophil-driven neoangiogenesis and promotes tissue regeneration via production of angiocrine factors in mice.
Tashiro Y, Nishida C, Sato-Kusubata K, Ohki-Koizumi M, Ishihara M, Sato A, Gritli I, Komiyama H, Sato Y, Dan T, Miyata T, Okumura K, Tomiki Y, Sakamoto K, Nakauchi H, Heissig B, Hattori K. Tashiro Y, et al. Among authors: gritli i. Blood. 2012 Jun 28;119(26):6382-93. doi: 10.1182/blood-2011-12-399659. Epub 2012 May 9. Blood. 2012. PMID: 22573404 Free article.
MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells.
Nishida C, Kusubata K, Tashiro Y, Gritli I, Sato A, Ohki-Koizumi M, Morita Y, Nagano M, Sakamoto T, Koshikawa N, Kuchimaru T, Kizaka-Kondoh S, Seiki M, Nakauchi H, Heissig B, Hattori K. Nishida C, et al. Among authors: gritli i. Blood. 2012 Jun 7;119(23):5405-16. doi: 10.1182/blood-2011-11-390849. Epub 2012 Apr 27. Blood. 2012. PMID: 22544701 Free article.
Plasmin inhibitor reduces T-cell lymphoid tumor growth by suppressing matrix metalloproteinase-9-dependent CD11b(+)/F4/80(+) myeloid cell recruitment.
Ishihara M, Nishida C, Tashiro Y, Gritli I, Rosenkvist J, Koizumi M, Okaji Y, Yamamoto R, Yagita H, Okumura K, Nishikori M, Wanaka K, Tsuda Y, Okada Y, Nakauchi H, Heissig B, Hattori K. Ishihara M, et al. Among authors: gritli i. Leukemia. 2012 Feb;26(2):332-9. doi: 10.1038/leu.2011.203. Epub 2011 Sep 20. Leukemia. 2012. PMID: 21931322
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