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Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.
Chia NY, Deng N, Das K, Huang D, Hu L, Zhu Y, Lim KH, Lee MH, Wu J, Sam XX, Tan GS, Wan WK, Yu W, Gan A, Tan AL, Tay ST, Soo KC, Wong WK, Dominguez LT, Ng HH, Rozen S, Goh LK, Teh BT, Tan P. Chia NY, et al. Among authors: wan wk. Gut. 2015 May;64(5):707-19. doi: 10.1136/gutjnl-2013-306596. Epub 2014 Jul 22. Gut. 2015. PMID: 25053715
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes.
Zang ZJ, Cutcutache I, Poon SL, Zhang SL, McPherson JR, Tao J, Rajasegaran V, Heng HL, Deng N, Gan A, Lim KH, Ong CK, Huang D, Chin SY, Tan IB, Ng CC, Yu W, Wu Y, Lee M, Wu J, Poh D, Wan WK, Rha SY, So J, Salto-Tellez M, Yeoh KG, Wong WK, Zhu YJ, Futreal PA, Pang B, Ruan Y, Hillmer AM, Bertrand D, Nagarajan N, Rozen S, Teh BT, Tan P. Zang ZJ, et al. Among authors: wan wk. Nat Genet. 2012 May;44(5):570-4. doi: 10.1038/ng.2246. Nat Genet. 2012. PMID: 22484628
An integrative approach identified genes associated with drug response in gastric cancer.
Zhou J, Yong WP, Yap CS, Vijayaraghavan A, Sinha RA, Singh BK, Xiu S, Manesh S, Ngo A, Lim A, Ang C, Xie C, Wong FY, Lin SJ, Wan WK, Tan IB, Flotow H, Tan P, Lim KH, Yen PM, Goh LK. Zhou J, et al. Among authors: wan wk. Carcinogenesis. 2015 Apr;36(4):441-51. doi: 10.1093/carcin/bgv014. Epub 2015 Mar 5. Carcinogenesis. 2015. PMID: 25742747
Extent of field change in colorectal cancers with BRAF mutation.
Poh A, Chang HS, Tan KY, Sam XX, Khoo A, Choo SN, Nga ME, Wan WK. Poh A, et al. Among authors: wan wk. Singapore Med J. 2018 Mar;59(3):139-143. doi: 10.11622/smedj.2017012. Epub 2017 Feb 17. Singapore Med J. 2018. PMID: 28210747 Free PMC article. Review.
GATA4 downregulation enhances CCL20-mediated immunosuppression in hepatocellular carcinoma.
Nasir NJM, Chuah S, Shuen T, Prawira A, Ba R, Lim MC, Chua J, Nguyen PHD, Lim CJ, Wasser M, Hazirah SN, Lim TKH, Leow WQ, Loh TJ, Wan WK, Pang YH, Soon G, Cheow PC, Kam JH, Iyer S, Kow A, Dan YY, Bonney GK, Chung A, Goh BKP, Chow PKH, Albani S, Zhai W, Ouyang JF, Toh HC, Chew V. Nasir NJM, et al. Among authors: wan wk. Hepatol Commun. 2024 Aug 19;8(9):e0508. doi: 10.1097/HC9.0000000000000508. eCollection 2024 Sep 1. Hepatol Commun. 2024. PMID: 39167427 Free PMC article.
Multi-region sampling with paired sample sequencing analyses reveals sub-groups of patients with novel patient-specific dysregulation in Hepatocellular Carcinoma.
Jeon AJ, Teo YY, Sekar K, Chong SL, Wu L, Chew SC, Chen J, Kendarsari RI, Lai H, Ling WH, Kaya NA, Lim JQ, Ramasamy A, Oguz G, Chung AY, Chan CY, Cheow PC, Kam JH, Madhavan K, Kow A, Ganpathi IS, Lim TKH, Leow WQ, Loong S, Loh TJ, Wan WK, Soon GST, Pang YH, Yoong BK, Ong DB, Lim J, de Villa VH, Cruz RDD, Chanwat R, Thammasiri J, Bonney GK, Goh BKP, Tucker-Kellogg G, Foo RSY, Chow PKH. Jeon AJ, et al. Among authors: wan wk. BMC Cancer. 2023 Feb 3;23(1):118. doi: 10.1186/s12885-022-10444-3. BMC Cancer. 2023. PMID: 36737737 Free PMC article.
CD30+OX40+ Treg is associated with improved overall survival in colorectal cancer.
Lam JH, Hong M, Koo SL, Chua CWL, Lim KL, Wee F, Wan WK, Leow WQ, Yeo JG, Tan IBH, Yeong J, Lim TKH, Lim TS. Lam JH, et al. Among authors: wan wk. Cancer Immunol Immunother. 2021 Aug;70(8):2353-2365. doi: 10.1007/s00262-021-02859-x. Epub 2021 Feb 2. Cancer Immunol Immunother. 2021. PMID: 33527196 Free PMC article.
56 results