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First-in-class oral small molecule inhibitor of the tyrosine kinase ROR1 (KAN0439834) induced significant apoptosis of chronic lymphocytic leukemia cells.
Hojjat-Farsangi M, Daneshmanesh AH, Khan AS, Shetye J, Mozaffari F, Kharaziha P, Rathje LS, Kokhaei P, Hansson L, Vågberg J, Byström S, Olsson E, Löfberg C, Norström C, Schultz J, Norin M, Olin T, Österborg A, Mellstedt H, Moshfegh A. Hojjat-Farsangi M, et al. Among authors: daneshmanesh ah. Leukemia. 2018 Oct;32(10):2291-2295. doi: 10.1038/s41375-018-0113-1. Epub 2018 Mar 27. Leukemia. 2018. PMID: 29725030 Free PMC article. No abstract available.
Silencing of ROR1 and FMOD with siRNA results in apoptosis of CLL cells.
Choudhury A, Derkow K, Daneshmanesh AH, Mikaelsson E, Kiaii S, Kokhaei P, Osterborg A, Mellstedt H. Choudhury A, et al. Among authors: daneshmanesh ah. Br J Haematol. 2010 Nov;151(4):327-35. doi: 10.1111/j.1365-2141.2010.08362.x. Epub 2010 Aug 31. Br J Haematol. 2010. PMID: 20813009 Free article.
Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies.
Daneshmanesh AH, Porwit A, Hojjat-Farsangi M, Jeddi-Tehrani M, Tamm KP, Grandér D, Lehmann S, Norin S, Shokri F, Rabbani H, Mellstedt H, Österborg A. Daneshmanesh AH, et al. Leuk Lymphoma. 2013 Apr;54(4):843-50. doi: 10.3109/10428194.2012.731599. Epub 2012 Oct 9. Leuk Lymphoma. 2013. PMID: 22988987
Inhibition of the receptor tyrosine kinase ROR1 by anti-ROR1 monoclonal antibodies and siRNA induced apoptosis of melanoma cells.
Hojjat-Farsangi M, Ghaemimanesh F, Daneshmanesh AH, Bayat AA, Mahmoudian J, Jeddi-Tehrani M, Rabbani H, Mellstedt H. Hojjat-Farsangi M, et al. Among authors: daneshmanesh ah. PLoS One. 2013 Apr 8;8(4):e61167. doi: 10.1371/journal.pone.0061167. Print 2013. PLoS One. 2013. Retraction in: PLoS One. 2022 May 5;17(5):e0268357. doi: 10.1371/journal.pone.0268357. PMID: 23593420 Free PMC article. Retracted.
Spontaneous Immunity Against the Receptor Tyrosine Kinase ROR1 in Patients with Chronic Lymphocytic Leukemia.
Hojjat-Farsangi M, Jeddi-Tehrani M, Daneshmanesh AH, Mozaffari F, Moshfegh A, Hansson L, Razavi SM, Sharifian RA, Rabbani H, Österborg A, Mellstedt H, Shokri F. Hojjat-Farsangi M, et al. Among authors: daneshmanesh ah. PLoS One. 2015 Nov 12;10(11):e0142310. doi: 10.1371/journal.pone.0142310. eCollection 2015. PLoS One. 2015. PMID: 26562161 Free PMC article.
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