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Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation.
Boudreau LH, Duchez AC, Cloutier N, Soulet D, Martin N, Bollinger J, Paré A, Rousseau M, Naika GS, Lévesque T, Laflamme C, Marcoux G, Lambeau G, Farndale RW, Pouliot M, Hamzeh-Cognasse H, Cognasse F, Garraud O, Nigrovic PA, Guderley H, Lacroix S, Thibault L, Semple JW, Gelb MH, Boilard E. Boudreau LH, et al. Among authors: lacroix s. Blood. 2014 Oct 2;124(14):2173-83. doi: 10.1182/blood-2014-05-573543. Epub 2014 Jul 31. Blood. 2014. PMID: 25082876 Free PMC article.
Platelets can enhance vascular permeability.
Cloutier N, Paré A, Farndale RW, Schumacher HR, Nigrovic PA, Lacroix S, Boilard E. Cloutier N, et al. Among authors: lacroix s. Blood. 2012 Aug 9;120(6):1334-43. doi: 10.1182/blood-2012-02-413047. Epub 2012 Apr 27. Blood. 2012. PMID: 22544703 Free article.
Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice.
Lévesque SA, Paré A, Mailhot B, Bellver-Landete V, Kébir H, Lécuyer MA, Alvarez JI, Prat A, de Rivero Vaccari JP, Keane RW, Lacroix S. Lévesque SA, et al. Among authors: lacroix s. J Exp Med. 2016 May 30;213(6):929-49. doi: 10.1084/jem.20151437. Epub 2016 May 2. J Exp Med. 2016. PMID: 27139491 Free PMC article.
Megakaryocytes compensate for Kit insufficiency in murine arthritis.
Cunin P, Penke LR, Thon JN, Monach PA, Jones T, Chang MH, Chen MM, Melki I, Lacroix S, Iwakura Y, Ware J, Gurish MF, Italiano JE, Boilard E, Nigrovic PA. Cunin P, et al. Among authors: lacroix s. J Clin Invest. 2017 May 1;127(5):1714-1724. doi: 10.1172/JCI84598. Epub 2017 Apr 4. J Clin Invest. 2017. PMID: 28375155 Free PMC article.
IL-1β enables CNS access to CCR2hi monocytes and the generation of pathogenic cells through GM-CSF released by CNS endothelial cells.
Paré A, Mailhot B, Lévesque SA, Juzwik C, Ignatius Arokia Doss PM, Lécuyer MA, Prat A, Rangachari M, Fournier A, Lacroix S. Paré A, et al. Among authors: lacroix s. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1194-E1203. doi: 10.1073/pnas.1714948115. Epub 2018 Jan 22. Proc Natl Acad Sci U S A. 2018. PMID: 29358392 Free PMC article.
215 results