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The DEXLIFE study methods: identifying novel candidate biomarkers that predict progression to type 2 diabetes in high risk individuals.
Andersen GS, Thybo T, Cederberg H, Orešič M, Esteller M, Zorzano A, Carr B, Walker M, Cobb J, Clissmann C, O'Gorman DJ, Nolan JJ; DEXLIFE Consortium. Andersen GS, et al. Diabetes Res Clin Pract. 2014 Nov;106(2):383-9. doi: 10.1016/j.diabres.2014.07.025. Epub 2014 Jul 27. Diabetes Res Clin Pract. 2014. PMID: 25125339 Clinical Trial.
Early-onset and classical forms of type 2 diabetes show impaired expression of genes involved in muscle branched-chain amino acids metabolism.
Hernández-Alvarez MI, Díaz-Ramos A, Berdasco M, Cobb J, Planet E, Cooper D, Pazderska A, Wanic K, O'Hanlon D, Gomez A, de la Ballina LR, Esteller M, Palacin M, O'Gorman DJ, Nolan JJ, Zorzano A. Hernández-Alvarez MI, et al. Sci Rep. 2017 Oct 23;7(1):13850. doi: 10.1038/s41598-017-14120-6. Sci Rep. 2017. PMID: 29062026 Free PMC article.
Phenotypic Responses to a Lifestyle Intervention Do Not Account for Inter-Individual Variability in Glucose Tolerance for Individuals at High Risk of Type 2 Diabetes.
O'Donoghue G, Kennedy A, Andersen GS, Carr B, Cleary S, Durkan E, Davis H, Færch K, Fitzpatrick P, Kenny H, McCaffrey N, Monedero J, Murphy E, Noone J, Suvitaival T, Thybo T, Wheeler M, Vistisen D, Nolan JJ, O'Gorman DJ. O'Donoghue G, et al. Front Physiol. 2019 Mar 26;10:317. doi: 10.3389/fphys.2019.00317. eCollection 2019. Front Physiol. 2019. PMID: 30971951 Free PMC article.
87 results