Hertz NT - Search Results

1

Drugging MYCN through an allosteric transition in Aurora kinase A.

Gustafson WC, Meyerowitz JG, Nekritz EA, Chen J, Benes C, Charron E, Simonds EF, Seeger R, Matthay KK, Hertz NT, Eilers M, Shokat KM, Weiss WA. Gustafson WC, et al. Among authors: hertz nt. Cancer Cell. 2014 Sep 8;26(3):414-427. doi: 10.1016/j.ccr.2014.07.015. Epub 2014 Aug 28. Cancer Cell. 2014. PMID: 25175806 Free PMC article.

2

A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1.

Hertz NT, Berthet A, Sos ML, Thorn KS, Burlingame AL, Nakamura K, Shokat KM. Hertz NT, et al. Cell. 2013 Aug 15;154(4):737-47. doi: 10.1016/j.cell.2013.07.030. Cell. 2013. PMID: 23953109 Free PMC article.

3

Development of a chemical genetic approach for human aurora B kinase identifies novel substrates of the chromosomal passenger complex.

Hengeveld RC, Hertz NT, Vromans MJ, Zhang C, Burlingame AL, Shokat KM, Lens SM. Hengeveld RC, et al. Among authors: hertz nt. Mol Cell Proteomics. 2012 May;11(5):47-59. doi: 10.1074/mcp.M111.013912. Epub 2012 Jan 20. Mol Cell Proteomics. 2012. PMID: 22267324 Free PMC article.

4

Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen.

Levin RS, Hertz NT, Burlingame AL, Shokat KM, Mukherjee S. Levin RS, et al. Among authors: hertz nt. Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):E4776-83. doi: 10.1073/pnas.1608355113. Epub 2016 Aug 1. Proc Natl Acad Sci U S A. 2016. PMID: 27482120 Free PMC article.

5

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK.

Brennan DF, Dar AC, Hertz NT, Chao WC, Burlingame AL, Shokat KM, Barford D. Brennan DF, et al. Among authors: hertz nt. Nature. 2011 Apr 21;472(7343):366-9. doi: 10.1038/nature09860. Epub 2011 Mar 27. Nature. 2011. PMID: 21441910

6

Chemical genetic approach for kinase-substrate mapping by covalent capture of thiophosphopeptides and analysis by mass spectrometry.

Hertz NT, Wang BT, Allen JJ, Zhang C, Dar AC, Burlingame AL, Shokat KM. Hertz NT, et al. Curr Protoc Chem Biol. 2010 Mar 1;2(1):15-36. doi: 10.1002/9780470559277.ch090201. Curr Protoc Chem Biol. 2010. PMID: 23836541 Free PMC article.

7

Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction.

Schaffer BE, Levin RS, Hertz NT, Maures TJ, Schoof ML, Hollstein PE, Benayoun BA, Banko MR, Shaw RJ, Shokat KM, Brunet A. Schaffer BE, et al. Among authors: hertz nt. Cell Metab. 2015 Nov 3;22(5):907-21. doi: 10.1016/j.cmet.2015.09.009. Epub 2015 Oct 8. Cell Metab. 2015. PMID: 26456332 Free PMC article.

8

Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development.

Ultanir SK, Hertz NT, Li G, Ge WP, Burlingame AL, Pleasure SJ, Shokat KM, Jan LY, Jan YN. Ultanir SK, et al. Among authors: hertz nt. Neuron. 2012 Mar 22;73(6):1127-42. doi: 10.1016/j.neuron.2012.01.019. Epub 2012 Mar 21. Neuron. 2012. PMID: 22445341 Free PMC article.

9

MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development.

Ultanir SK, Yadav S, Hertz NT, Oses-Prieto JA, Claxton S, Burlingame AL, Shokat KM, Jan LY, Jan YN. Ultanir SK, et al. Among authors: hertz nt. Neuron. 2014 Dec 3;84(5):968-82. doi: 10.1016/j.neuron.2014.10.025. Epub 2014 Nov 13. Neuron. 2014. PMID: 25456499 Free PMC article.

10

Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease.

Orr AL, Rutaganira FU, de Roulet D, Huang EJ, Hertz NT, Shokat KM, Nakamura K. Orr AL, et al. Among authors: hertz nt. Neurochem Int. 2017 Oct;109:106-116. doi: 10.1016/j.neuint.2017.04.006. Epub 2017 Apr 20. Neurochem Int. 2017. PMID: 28434973 Free PMC article.

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