Mabuchi MY - Search Results

1

Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix.

Horton JR, Wang H, Mabuchi MY, Zhang X, Roberts RJ, Zheng Y, Wilson GG, Cheng X. Horton JR, et al. Among authors: mabuchi my. Nucleic Acids Res. 2014 Oct 29;42(19):12092-101. doi: 10.1093/nar/gku871. Epub 2014 Sep 27. Nucleic Acids Res. 2014. PMID: 25262349 Free PMC article.

2

Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease.

Horton JR, Mabuchi MY, Cohen-Karni D, Zhang X, Griggs RM, Samaranayake M, Roberts RJ, Zheng Y, Cheng X. Horton JR, et al. Among authors: mabuchi my. Nucleic Acids Res. 2012 Oct;40(19):9763-73. doi: 10.1093/nar/gks719. Epub 2012 Jul 30. Nucleic Acids Res. 2012. PMID: 22848107 Free PMC article.

3

Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHI.

Horton JR, Nugent RL, Li A, Mabuchi MY, Fomenkov A, Cohen-Karni D, Griggs RM, Zhang X, Wilson GG, Zheng Y, Xu SY, Cheng X. Horton JR, et al. Among authors: mabuchi my. Sci Rep. 2014 Mar 7;4:4246. doi: 10.1038/srep04246. Sci Rep. 2014. PMID: 24604015 Free PMC article.

4

A protein architecture guided screen for modification dependent restriction endonucleases.

Lutz T, Flodman K, Copelas A, Czapinska H, Mabuchi M, Fomenkov A, He X, Bochtler M, Xu SY. Lutz T, et al. Nucleic Acids Res. 2019 Oct 10;47(18):9761-9776. doi: 10.1093/nar/gkz755. Nucleic Acids Res. 2019. PMID: 31504772 Free PMC article.

5

DNA rehybridization drives product release from Cas9 ribonucleoprotein to enable multiple-turnover cleavage.

Pan J, Mabuchi M, Robb GB. Pan J, et al. Nucleic Acids Res. 2023 May 8;51(8):3903-3917. doi: 10.1093/nar/gkad233. Nucleic Acids Res. 2023. PMID: 37014013 Free PMC article.

6

Characterization of Cme and Yme thermostable Cas12a orthologs.

Fuchs RT, Curcuru JL, Mabuchi M, Noireterre A, Weigele PR, Sun Z, Robb GB. Fuchs RT, et al. Commun Biol. 2022 Apr 6;5(1):325. doi: 10.1038/s42003-022-03275-2. Commun Biol. 2022. PMID: 35388146 Free PMC article.

7

Staphylococcus aureus Cas9 is a multiple-turnover enzyme.

Yourik P, Fuchs RT, Mabuchi M, Curcuru JL, Robb GB. Yourik P, et al. RNA. 2019 Jan;25(1):35-44. doi: 10.1261/rna.067355.118. Epub 2018 Oct 22. RNA. 2019. PMID: 30348755 Free PMC article.

8

A catalogue of biochemically diverse CRISPR-Cas9 orthologs.

Gasiunas G, Young JK, Karvelis T, Kazlauskas D, Urbaitis T, Jasnauskaite M, Grusyte MM, Paulraj S, Wang PH, Hou Z, Dooley SK, Cigan M, Alarcon C, Chilcoat ND, Bigelyte G, Curcuru JL, Mabuchi M, Sun Z, Fuchs RT, Schildkraut E, Weigele PR, Jack WE, Robb GB, Venclovas Č, Siksnys V. Gasiunas G, et al. Nat Commun. 2020 Nov 2;11(1):5512. doi: 10.1038/s41467-020-19344-1. Nat Commun. 2020. PMID: 33139742 Free PMC article.

9

Precise DNA cleavage using CRISPR-SpRYgests.

Christie KA, Guo JA, Silverstein RA, Doll RM, Mabuchi M, Stutzman HE, Lin J, Ma L, Walton RT, Pinello L, Robb GB, Kleinstiver BP. Christie KA, et al. Nat Biotechnol. 2023 Mar;41(3):409-416. doi: 10.1038/s41587-022-01492-y. Epub 2022 Oct 6. Nat Biotechnol. 2023. PMID: 36203014 Free PMC article.

10

Target-dependent nickase activities of the CRISPR-Cas nucleases Cpf1 and Cas9.

Fu BXH, Smith JD, Fuchs RT, Mabuchi M, Curcuru J, Robb GB, Fire AZ. Fu BXH, et al. Nat Microbiol. 2019 May;4(5):888-897. doi: 10.1038/s41564-019-0382-0. Epub 2019 Mar 4. Nat Microbiol. 2019. PMID: 30833733 Free PMC article.

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