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A20 controls intestinal homeostasis through cell-specific activities.
Vereecke L, Vieira-Silva S, Billiet T, van Es JH, Mc Guire C, Slowicka K, Sze M, van den Born M, De Hertogh G, Clevers H, Raes J, Rutgeerts P, Vermeire S, Beyaert R, van Loo G. Vereecke L, et al. Among authors: slowicka k. Nat Commun. 2014 Sep 30;5:5103. doi: 10.1038/ncomms6103. Nat Commun. 2014. PMID: 25267258 Free article.
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities.
Martens A, Priem D, Hoste E, Vetters J, Rennen S, Catrysse L, Voet S, Deelen L, Sze M, Vikkula H, Slowicka K, Hochepied T, Iliaki K, Wullaert A, Janssens S, Lamkanfi M, Beyaert R, Armaka M, Bertrand MJM, van Loo G. Martens A, et al. Among authors: slowicka k. Nat Immunol. 2020 Apr;21(4):381-387. doi: 10.1038/s41590-020-0621-9. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205881
Zeb2 drives invasive and microbiota-dependent colon carcinoma.
Slowicka K, Petta I, Blancke G, Hoste E, Dumas E, Sze M, Vikkula H, Radaelli E, Haigh JJ, Jonckheere S, Taminau J, Vandamme N, Wullaert A, Tulchinsky E, Nittner D, Van Vlierberghe P, De Hertogh G, Baldin P, Etlioglu E, Wirapati P, Boon L, Lambrecht BN, Callewaert C, Tejpar S, Goossens S, Berx G, Vereecke L, van Loo G. Slowicka K, et al. Nat Cancer. 2020 Jun;1(6):620-634. doi: 10.1038/s43018-020-0070-2. Epub 2020 Jun 15. Nat Cancer. 2020. PMID: 35121975
A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism.
Catrysse L, Maes B, Mehrotra P, Martens A, Hoste E, Martens L, Maueröder C, Remmerie A, Bujko A, Slowicka K, Sze M, Vikkula H, Ghesquière B, Scott CL, Saeys Y, van de Sluis B, Ravichandran K, Janssens S, van Loo G. Catrysse L, et al. Among authors: slowicka k. Cell Rep. 2021 Sep 21;36(12):109748. doi: 10.1016/j.celrep.2021.109748. Cell Rep. 2021. PMID: 34551300 Free article.
Cellular Functions of Optineurin in Health and Disease.
Slowicka K, Vereecke L, van Loo G. Slowicka K, et al. Trends Immunol. 2016 Sep;37(9):621-633. doi: 10.1016/j.it.2016.07.002. Epub 2016 Jul 30. Trends Immunol. 2016. PMID: 27480243 Review.
Optineurin Functions for Optimal Immunity.
Slowicka K, van Loo G. Slowicka K, et al. Front Immunol. 2018 Apr 10;9:769. doi: 10.3389/fimmu.2018.00769. eCollection 2018. Front Immunol. 2018. PMID: 29692786 Free PMC article. Review.
15 results