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PDE5 inhibitors enhance celecoxib killing in multiple tumor types.
Booth L, Roberts JL, Cruickshanks N, Tavallai S, Webb T, Samuel P, Conley A, Binion B, Young HF, Poklepovic A, Spiegel S, Dent P. Booth L, et al. Among authors: spiegel s. J Cell Physiol. 2015 May;230(5):1115-27. doi: 10.1002/jcp.24843. J Cell Physiol. 2015. PMID: 25303541 Free PMC article.
The histone deacetylase inhibitor LAQ824 induces human leukemia cell death through a process involving XIAP down-regulation, oxidative injury, and the acid sphingomyelinase-dependent generation of ceramide.
Rosato RR, Maggio SC, Almenara JA, Payne SG, Atadja P, Spiegel S, Dent P, Grant S. Rosato RR, et al. Among authors: spiegel s. Mol Pharmacol. 2006 Jan;69(1):216-25. doi: 10.1124/mol.105.017145. Epub 2005 Sep 27. Mol Pharmacol. 2006. Retraction in: Mol Pharmacol. 2019 Apr;95(4):336. doi: 10.1124/mol.105.017145retraction. PMID: 16189296 Retracted.
OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells.
Park MA, Yacoub A, Rahmani M, Zhang G, Hart L, Hagan MP, Calderwood SK, Sherman MY, Koumenis C, Spiegel S, Chen CS, Graf M, Curiel DT, Fisher PB, Grant S, Dent P. Park MA, et al. Among authors: spiegel s. Mol Pharmacol. 2008 Apr;73(4):1168-84. doi: 10.1124/mol.107.042697. Epub 2008 Jan 8. Mol Pharmacol. 2008. PMID: 18182481 Free PMC article.
Caspase-, cathepsin-, and PERK-dependent regulation of MDA-7/IL-24-induced cell killing in primary human glioma cells.
Yacoub A, Park MA, Gupta P, Rahmani M, Zhang G, Hamed H, Hanna D, Sarkar D, Lebedeva IV, Emdad L, Sauane M, Vozhilla N, Spiegel S, Koumenis C, Graf M, Curiel DT, Grant S, Fisher PB, Dent P. Yacoub A, et al. Among authors: spiegel s. Mol Cancer Ther. 2008 Feb;7(2):297-313. doi: 10.1158/1535-7163.MCT-07-2166. Mol Cancer Ther. 2008. PMID: 18281515 Free PMC article.
496 results