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Engineering allostery.
Raman S, Taylor N, Genuth N, Fields S, Church GM. Raman S, et al. Among authors: church gm. Trends Genet. 2014 Dec;30(12):521-8. doi: 10.1016/j.tig.2014.09.004. Epub 2014 Oct 8. Trends Genet. 2014. PMID: 25306102 Free PMC article. Review.
Cas9 as a versatile tool for engineering biology.
Mali P, Esvelt KM, Church GM. Mali P, et al. Among authors: church gm. Nat Methods. 2013 Oct;10(10):957-63. doi: 10.1038/nmeth.2649. Nat Methods. 2013. PMID: 24076990 Free PMC article. Review.
Evolution-guided optimization of biosynthetic pathways.
Raman S, Rogers JK, Taylor ND, Church GM. Raman S, et al. Among authors: church gm. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17803-8. doi: 10.1073/pnas.1409523111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453111 Free PMC article.
Engineering an allosteric transcription factor to respond to new ligands.
Taylor ND, Garruss AS, Moretti R, Chan S, Arbing MA, Cascio D, Rogers JK, Isaacs FJ, Kosuri S, Baker D, Fields S, Church GM, Raman S. Taylor ND, et al. Among authors: church gm. Nat Methods. 2016 Feb;13(2):177-83. doi: 10.1038/nmeth.3696. Epub 2015 Dec 21. Nat Methods. 2016. PMID: 26689263 Free PMC article.
A general strategy to construct small molecule biosensors in eukaryotes.
Feng J, Jester BW, Tinberg CE, Mandell DJ, Antunes MS, Chari R, Morey KJ, Rios X, Medford JI, Church GM, Fields S, Baker D. Feng J, et al. Among authors: church gm. Elife. 2015 Dec 29;4:e10606. doi: 10.7554/eLife.10606. Elife. 2015. PMID: 26714111 Free PMC article.
Multiplexed Engineering in Biology.
Rogers JK, Church GM. Rogers JK, et al. Among authors: church gm. Trends Biotechnol. 2016 Mar;34(3):198-206. doi: 10.1016/j.tibtech.2015.12.004. Trends Biotechnol. 2016. PMID: 26897356 Review.
Biosensor-based engineering of biosynthetic pathways.
Rogers JK, Taylor ND, Church GM. Rogers JK, et al. Among authors: church gm. Curr Opin Biotechnol. 2016 Dec;42:84-91. doi: 10.1016/j.copbio.2016.03.005. Epub 2016 Mar 18. Curr Opin Biotechnol. 2016. PMID: 26998575 Free article. Review.
616 results