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Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.
Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H. Liu X, et al. Among authors: chen h. Sci Signal. 2014 Oct 14;7(347):ra97. doi: 10.1126/scisignal.2005413. Sci Signal. 2014. PMID: 25314967 Free PMC article.
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2.
Herzog BH, Fu J, Wilson SJ, Hess PR, Sen A, McDaniel JM, Pan Y, Sheng M, Yago T, Silasi-Mansat R, McGee S, May F, Nieswandt B, Morris AJ, Lupu F, Coughlin SR, McEver RP, Chen H, Kahn ML, Xia L. Herzog BH, et al. Among authors: chen h. Nature. 2013 Oct 3;502(7469):105-9. doi: 10.1038/nature12501. Epub 2013 Sep 1. Nature. 2013. PMID: 23995678 Free PMC article.
Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.
Tessneer KL, Pasula S, Cai X, Dong Y, McManus J, Liu X, Yu L, Hahn S, Chang B, Chen Y, Griffin C, Xia L, Adams RH, Chen H. Tessneer KL, et al. Among authors: chen h, chen y. Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):331-337. doi: 10.1161/ATVBAHA.113.302586. Epub 2013 Dec 5. Arterioscler Thromb Vasc Biol. 2014. PMID: 24311377 Free PMC article.
Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.
Song K, Herzog BH, Fu J, Sheng M, Bergstrom K, McDaniel JM, Kondo Y, McGee S, Cai X, Li P, Chen H, Xia L. Song K, et al. Among authors: chen h. J Biol Chem. 2015 Aug 14;290(33):20159-66. doi: 10.1074/jbc.M115.654483. Epub 2015 Jun 29. J Biol Chem. 2015. PMID: 26124270 Free PMC article.
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