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A single intramuscular vaccination of mice with the HSV-1 VC2 virus with mutations in the glycoprotein K and the membrane protein UL20 confers full protection against lethal intravaginal challenge with virulent HSV-1 and HSV-2 strains.
Stanfield BA, Stahl J, Chouljenko VN, Subramanian R, Charles AS, Saied AA, Walker JD, Kousoulas KG. Stanfield BA, et al. Among authors: saied aa. PLoS One. 2014 Oct 28;9(10):e109890. doi: 10.1371/journal.pone.0109890. eCollection 2014. PLoS One. 2014. PMID: 25350288 Free PMC article.
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