Haass C - Search Results

1

Shedding of glycan-modifying enzymes by signal peptide peptidase-like 3 (SPPL3) regulates cellular N-glycosylation.

Voss M, Künzel U, Higel F, Kuhn PH, Colombo A, Fukumori A, Haug-Kröper M, Klier B, Grammer G, Seidl A, Schröder B, Obst R, Steiner H, Lichtenthaler SF, Haass C, Fluhrer R. Voss M, et al. Among authors: haass c. EMBO J. 2014 Dec 17;33(24):2890-905. doi: 10.15252/embj.201488375. Epub 2014 Oct 29. EMBO J. 2014. PMID: 25354954 Free PMC article.

2

Proteolytic processing and degradation of Alzheimer's disease relevant proteins.

Steiner H, Capell A, Haass C. Steiner H, et al. Among authors: haass c. Biochem Soc Trans. 1999 Feb;27(2):234-42. doi: 10.1042/bst0270234. Biochem Soc Trans. 1999. PMID: 10093740 Review. No abstract available.

3

An in vivo assay for the identification of target proteases which cleave membrane-associated substrates.

Steiner H, Pesold B, Haass C. Steiner H, et al. Among authors: haass c. FEBS Lett. 1999 Dec 17;463(3):245-9. doi: 10.1016/s0014-5793(99)01627-0. FEBS Lett. 1999. PMID: 10606730 Free article.

4

Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.

Steiner H, Capell A, Leimer U, Haass C. Steiner H, et al. Among authors: haass c. Eur Arch Psychiatry Clin Neurosci. 1999;249(6):266-70. doi: 10.1007/s004060050098. Eur Arch Psychiatry Clin Neurosci. 1999. PMID: 10653281 Review.

5

Presenilin-1 differentially facilitates endoproteolysis of the beta-amyloid precursor protein and Notch.

Capell A, Steiner H, Romig H, Keck S, Baader M, Grim MG, Baumeister R, Haass C. Capell A, et al. Among authors: haass c. Nat Cell Biol. 2000 Apr;2(4):205-11. doi: 10.1038/35008626. Nat Cell Biol. 2000. PMID: 10783238

6

Maturation and pro-peptide cleavage of beta-secretase.

Capell A, Steiner H, Willem M, Kaiser H, Meyer C, Walter J, Lammich S, Multhaup G, Haass C. Capell A, et al. Among authors: haass c. J Biol Chem. 2000 Oct 6;275(40):30849-54. doi: 10.1074/jbc.M003202200. J Biol Chem. 2000. PMID: 10801872 Free article.

7

Separation of presenilin function in amyloid beta-peptide generation and endoproteolysis of Notch.

Kulic L, Walter J, Multhaup G, Teplow DB, Baumeister R, Romig H, Capell A, Steiner H, Haass C. Kulic L, et al. Among authors: haass c. Proc Natl Acad Sci U S A. 2000 May 23;97(11):5913-8. doi: 10.1073/pnas.100049897. Proc Natl Acad Sci U S A. 2000. PMID: 10811883 Free PMC article.

8

Mutation of conserved aspartates affects maturation of both aspartate mutant and endogenous presenilin 1 and presenilin 2 complexes.

Yu G, Chen F, Nishimura M, Steiner H, Tandon A, Kawarai T, Arawaka S, Supala A, Song YQ, Rogaeva E, Holmes E, Zhang DM, Milman P, Fraser PE, Haass C, George-Hyslop PS. Yu G, et al. Among authors: haass c. J Biol Chem. 2000 Sep 1;275(35):27348-53. doi: 10.1074/jbc.M002982200. J Biol Chem. 2000. PMID: 10856299 Free article.

9

A loss of function mutant of the presenilin homologue SEL-12 undergoes aberrant endoproteolysis in Caenorhabditis elegans and increases abeta 42 generation in human cells.

Okochi M, Eimer S, Bottcher A, Baumeister R, Romig H, Walter J, Capell A, Steiner H, Haass C. Okochi M, et al. Among authors: haass c. J Biol Chem. 2000 Dec 29;275(52):40925-32. doi: 10.1074/jbc.M005254200. J Biol Chem. 2000. PMID: 11013240 Free article.

10

Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases.

Steiner H, Kostka M, Romig H, Basset G, Pesold B, Hardy J, Capell A, Meyn L, Grim ML, Baumeister R, Fechteler K, Haass C. Steiner H, et al. Among authors: haass c. Nat Cell Biol. 2000 Nov;2(11):848-51. doi: 10.1038/35041097. Nat Cell Biol. 2000. PMID: 11056541

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