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miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response.
Wallace JA, Kagele DA, Eiring AM, Kim CN, Hu R, Runtsch MC, Alexander M, Huffaker TB, Lee SH, Patel AB, Mosbruger TL, Voth WP, Rao DS, Miles RR, Round JL, Deininger MW, O'Connell RM. Wallace JA, et al. Among authors: alexander m. Blood. 2017 Jun 8;129(23):3074-3086. doi: 10.1182/blood-2016-09-740209. Epub 2017 Apr 21. Blood. 2017. PMID: 28432220 Free PMC article.
Antitumor immunity is defective in T cell-specific microRNA-155-deficient mice and is rescued by immune checkpoint blockade.
Huffaker TB, Lee SH, Tang WW, Wallace JA, Alexander M, Runtsch MC, Larsen DK, Thompson J, Ramstead AG, Voth WP, Hu R, Round JL, Williams MA, O'Connell RM. Huffaker TB, et al. Among authors: alexander m. J Biol Chem. 2017 Nov 10;292(45):18530-18541. doi: 10.1074/jbc.M117.808121. Epub 2017 Sep 14. J Biol Chem. 2017. PMID: 28912267 Free PMC article.
Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease.
Runtsch MC, Nelson MC, Lee SH, Voth W, Alexander M, Hu R, Wallace J, Petersen C, Panic V, Villanueva CJ, Evason KJ, Bauer KM, Mosbruger T, Boudina S, Bronner M, Round JL, Drummond MJ, O'Connell RM. Runtsch MC, et al. Among authors: alexander m. PLoS Genet. 2019 Feb 15;15(2):e1007970. doi: 10.1371/journal.pgen.1007970. eCollection 2019 Feb. PLoS Genet. 2019. PMID: 30768595 Free PMC article.
CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis.
Bauer KM, Nelson MC, Tang WW, Chiaro TR, Brown DG, Ghazaryan A, Lee SH, Weis AM, Hill JH, Klag KA, Tran VB, Thompson JW, Ramstead AG, Monts JK, Marvin JE, Alexander M, Voth WP, Stephens WZ, Ward DM, Petrey AC, Round JL, O'Connell RM. Bauer KM, et al. Among authors: alexander m. JCI Insight. 2022 Oct 10;7(19):e159469. doi: 10.1172/jci.insight.159469. JCI Insight. 2022. PMID: 36214220 Free PMC article.
3,567 results