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Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism.
Zanin-Zhorov A, Weiss JM, Nyuydzefe MS, Chen W, Scher JU, Mo R, Depoil D, Rao N, Liu B, Wei J, Lucas S, Koslow M, Roche M, Schueller O, Weiss S, Poyurovsky MV, Tonra J, Hippen KL, Dustin ML, Blazar BR, Liu CJ, Waksal SD. Zanin-Zhorov A, et al. Among authors: lucas s. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16814-9. doi: 10.1073/pnas.1414189111. Epub 2014 Nov 10. Proc Natl Acad Sci U S A. 2014. PMID: 25385601 Free PMC article.
Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling.
Tremblay CS, Brown FC, Collett M, Saw J, Chiu SK, Sonderegger SE, Lucas SE, Alserihi R, Chau N, Toribio ML, McCormack MP, Chircop M, Robinson PJ, Jane SM, Curtis DJ. Tremblay CS, et al. Among authors: lucas se. Leukemia. 2016 Oct;30(10):1993-2001. doi: 10.1038/leu.2016.100. Epub 2016 Apr 27. Leukemia. 2016. PMID: 27118408
Controls on spatial variation in porewater methane concentrations across United States tidal wetlands.
Koontz EL, Parker SM, Stearns AE, Roberts BJ, Young CM, Windham-Myers L, Oikawa PY, Megonigal JP, Noyce GL, Buskey EJ, Derby RK, Dunn RP, Ferner MC, Krask JL, Marconi CM, Savage KB, Shahan J, Spivak AC, St Laurent K, Argueta JM, Baird SJ, Beheshti KM, Crane LC, Cressman KA, Crooks JA, Fernald SH, Garwood JA, Goldstein JS, Grothues TM, Habeck A, Lerberg SB, Lucas SB, Marcum P, Peter CR, Phipps SW, Raposa KB, Rovai AS, Schooler SS, Twilley RR, Tyrrell MC, Uyeda KA, Wulfing SH, Aman JT, Giacchetti A, Cross-Johnson SN, Holmquist JR. Koontz EL, et al. Among authors: lucas sb. Sci Total Environ. 2024 Nov 2:177290. doi: 10.1016/j.scitotenv.2024.177290. Online ahead of print. Sci Total Environ. 2024. PMID: 39491559
Preclinical development of SGN-CD47M: Protease-activated antibody technology enables selective tumor targeting of the innate immune checkpoint receptor CD47.
Levengood MR, Carosino CM, Zhang X, Lucas S, Ortiz DJ, Westendorf L, Chin AP, Martin AD, Wong A, Hengel SM, Sun H, Zeng W, Yumul R, Dominguez MM, Chen Y, Zheng JH, Karlsson CAB, Trang VH, Senter PD, Gardai SJ. Levengood MR, et al. Among authors: lucas s. Mol Cancer Ther. 2024 Oct 28. doi: 10.1158/1535-7163.MCT-24-0371. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39463068
The Environmental Impact of a High-Altitude Medical Research Expedition.
Joyce KE, Campbell CA, Bradwell AR, Lucas SJE, Lewis CT, Lucas RAI, Edsell M; Birmingham Medical Research Expeditionary Society (BMRES). Joyce KE, et al. Among authors: lucas sje. High Alt Med Biol. 2024 Oct 25. doi: 10.1089/ham.2024.0049. Online ahead of print. High Alt Med Biol. 2024. PMID: 39453624
1,796 results