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Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis.
Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH. Wilkins HM, et al. Among authors: carl sm. Hum Mol Genet. 2014 Dec 15;23(24):6528-41. doi: 10.1093/hmg/ddu371. Epub 2014 Jul 15. Hum Mol Genet. 2014. PMID: 25027327 Free PMC article.
Oxaloacetate enhances neuronal cell bioenergetic fluxes and infrastructure.
Wilkins HM, Koppel S, Carl SM, Ramanujan S, Weidling I, Michaelis ML, Michaelis EK, Swerdlow RH. Wilkins HM, et al. Among authors: carl sm. J Neurochem. 2016 Apr;137(1):76-87. doi: 10.1111/jnc.13545. Epub 2016 Mar 11. J Neurochem. 2016. PMID: 26811028 Free PMC article.
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