Granholm AC - Search Results

1

Down syndrome and Alzheimer's disease: Common pathways, common goals.

Hartley D, Blumenthal T, Carrillo M, DiPaolo G, Esralew L, Gardiner K, Granholm AC, Iqbal K, Krams M, Lemere C, Lott I, Mobley W, Ness S, Nixon R, Potter H, Reeves R, Sabbagh M, Silverman W, Tycko B, Whitten M, Wisniewski T. Hartley D, et al. Among authors: granholm ac. Alzheimers Dement. 2015 Jun;11(6):700-9. doi: 10.1016/j.jalz.2014.10.007. Epub 2014 Dec 12. Alzheimers Dement. 2015. PMID: 25510383 Free PMC article.

2

Regional alterations in amyloid precursor protein and nerve growth factor across age in a mouse model of Down's syndrome.

Hunter CL, Isacson O, Nelson M, Bimonte-Nelson H, Seo H, Lin L, Ford K, Kindy MS, Granholm AC. Hunter CL, et al. Among authors: granholm ac. Neurosci Res. 2003 Apr;45(4):437-45. doi: 10.1016/s0168-0102(03)00005-1. Neurosci Res. 2003. PMID: 12657457

3

Estrogen alters amyloid precursor protein as well as dendritic and cholinergic markers in a mouse model of Down syndrome.

Granholm AC, Sanders L, Seo H, Lin L, Ford K, Isacson O. Granholm AC, et al. Hippocampus. 2003;13(8):905-14. doi: 10.1002/hipo.10130. Hippocampus. 2003. PMID: 14750653

4

Behavioral and neurobiological markers of Alzheimer's disease in Ts65Dn mice: effects of estrogen.

Hunter CL, Bimonte-Nelson HA, Nelson M, Eckman CB, Granholm AC. Hunter CL, et al. Among authors: granholm ac. Neurobiol Aging. 2004 Aug;25(7):873-84. doi: 10.1016/j.neurobiolaging.2003.10.010. Neurobiol Aging. 2004. PMID: 15212841

5

Minocycline prevents cholinergic loss in a mouse model of Down's syndrome.

Hunter CL, Bachman D, Granholm AC. Hunter CL, et al. Among authors: granholm ac. Ann Neurol. 2004 Nov;56(5):675-88. doi: 10.1002/ana.20250. Ann Neurol. 2004. PMID: 15468085

6

Nerve growth factor in treatment and pathogenesis of Alzheimer's disease.

Williams BJ, Eriksdotter-Jonhagen M, Granholm AC. Williams BJ, et al. Among authors: granholm ac. Prog Neurobiol. 2006 Oct;80(3):114-28. doi: 10.1016/j.pneurobio.2006.09.001. Epub 2006 Nov 2. Prog Neurobiol. 2006. PMID: 17084014 Review.

7

Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model.

Lockrow J, Prakasam A, Huang P, Bimonte-Nelson H, Sambamurti K, Granholm AC. Lockrow J, et al. Among authors: granholm ac. Exp Neurol. 2009 Apr;216(2):278-89. doi: 10.1016/j.expneurol.2008.11.021. Epub 2008 Dec 10. Exp Neurol. 2009. PMID: 19135442 Free PMC article.

8

Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, Luigi Puglielli.

Granholm AC, Bachman D, Mintzer J, Sambamurti K. Granholm AC, et al. Alzheimers Dement. 2005 Jul;1(1):53-4. doi: 10.1016/j.jalz.2005.06.010. Alzheimers Dement. 2005. PMID: 19595818 No abstract available.

9

A noradrenergic lesion exacerbates neurodegeneration in a Down syndrome mouse model.

Lockrow J, Boger H, Gerhardt G, Aston-Jones G, Bachman D, Granholm AC. Lockrow J, et al. Among authors: granholm ac. J Alzheimers Dis. 2011;23(3):471-89. doi: 10.3233/JAD-2010-101218. J Alzheimers Dis. 2011. PMID: 21098982 Free PMC article.

10

Nerve growth factor metabolic dysfunction in Down's syndrome brains.

Iulita MF, Do Carmo S, Ower AK, Fortress AM, Flores Aguilar L, Hanna M, Wisniewski T, Granholm AC, Buhusi M, Busciglio J, Cuello AC. Iulita MF, et al. Among authors: granholm ac. Brain. 2014 Mar;137(Pt 3):860-72. doi: 10.1093/brain/awt372. Epub 2014 Feb 11. Brain. 2014. PMID: 24519975 Free PMC article.

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