Mobley W - Search Results

1

Down syndrome and Alzheimer's disease: Common pathways, common goals.

Hartley D, Blumenthal T, Carrillo M, DiPaolo G, Esralew L, Gardiner K, Granholm AC, Iqbal K, Krams M, Lemere C, Lott I, Mobley W, Ness S, Nixon R, Potter H, Reeves R, Sabbagh M, Silverman W, Tycko B, Whitten M, Wisniewski T. Hartley D, et al. Among authors: mobley w. Alzheimers Dement. 2015 Jun;11(6):700-9. doi: 10.1016/j.jalz.2014.10.007. Epub 2014 Dec 12. Alzheimers Dement. 2015. PMID: 25510383 Free PMC article.

2

Modeling cholinergic abnormalities in Down syndrome and Alzheimer's disease.

Holtzman DM, Li YW, Gage FH, DeArmond SJ, Epstein CJ, McKinley MP, Mobley WC. Holtzman DM, et al. Among authors: mobley wc. Prog Clin Biol Res. 1991;373:189-202. Prog Clin Biol Res. 1991. PMID: 1838184 No abstract available.

3

Molecular studies in Alzheimer's disease.

Holtzman DM, Mobley WC. Holtzman DM, et al. Among authors: mobley wc. Trends Biochem Sci. 1991 Apr;16(4):140-4. doi: 10.1016/0968-0004(91)90056-2. Trends Biochem Sci. 1991. PMID: 1877089 Review.

4

Nerve growth factor in Alzheimer's disease: to treat or not to treat?

Mobley WC. Mobley WC. Neurobiol Aging. 1989 Sep-Oct;10(5):578-80; discussion 588-90. doi: 10.1016/0197-4580(89)90135-8. Neurobiol Aging. 1989. PMID: 2812231

5

Report on the 'Expert Workshop on the Biology of Chromosome 21: towards gene-phenotype correlations in Down syndrome', held June 11-14, 2004, Washington D.C.

Gardiner K, Davisson MT, Pritchard M, Patterson D, Groner Y, Crnic LS, Antonarakis S, Mobley W. Gardiner K, et al. Among authors: mobley w. Cytogenet Genome Res. 2005;108(4):269-77. doi: 10.1159/000081518. Cytogenet Genome Res. 2005. PMID: 15627744 No abstract available.

6

Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, Lamb BT, Epstein CJ, Stokin GB, Goldstein LS, Mobley WC. Salehi A, et al. Among authors: mobley wc. Neuron. 2006 Jul 6;51(1):29-42. doi: 10.1016/j.neuron.2006.05.022. Neuron. 2006. PMID: 16815330 Free article.

7

The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome.

Belichenko NP, Belichenko PV, Kleschevnikov AM, Salehi A, Reeves RH, Mobley WC. Belichenko NP, et al. J Neurosci. 2009 May 6;29(18):5938-48. doi: 10.1523/JNEUROSCI.1547-09.2009. J Neurosci. 2009. PMID: 19420260 Free PMC article.

8

Implications for treatment: GABAA receptors in aging, Down syndrome and Alzheimer's disease.

Rissman RA, Mobley WC. Rissman RA, et al. J Neurochem. 2011 May;117(4):613-22. doi: 10.1111/j.1471-4159.2011.07237.x. Epub 2011 Mar 28. J Neurochem. 2011. PMID: 21388375 Free PMC article. Review.

9

Mouse models for Down syndrome-associated developmental cognitive disabilities.

Liu C, Belichenko PV, Zhang L, Fu D, Kleschevnikov AM, Baldini A, Antonarakis SE, Mobley WC, Yu YE. Liu C, et al. Dev Neurosci. 2011;33(5):404-13. doi: 10.1159/000329422. Epub 2011 Aug 25. Dev Neurosci. 2011. PMID: 21865664 Free PMC article. Review.

10

Recent Perspectives on APP, Secretases, Endosomal Pathways and How they Influence Alzheimer's Related Pathological Changes in Down Syndrome.

Decourt B, Mobley W, Reiman E, Shah RJ, Sabbagh MN. Decourt B, et al. Among authors: mobley w. J Alzheimers Dis Parkinsonism. 2013 Mar 20;Suppl 7:002. doi: 10.4172/2161-0460.S7-002. J Alzheimers Dis Parkinsonism. 2013. PMID: 24782952 Free PMC article.

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