He S - Search Results

1

A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing.

Gjini E, Mansour MR, Sander JD, Moritz N, Nguyen AT, Kesarsing M, Gans E, He S, Chen S, Ko M, Kuang YY, Yang S, Zhou Y, Rodig S, Zon LI, Joung JK, Rao A, Look AT. Gjini E, et al. Among authors: he s. Mol Cell Biol. 2015 Mar;35(5):789-804. doi: 10.1128/MCB.00971-14. Epub 2014 Dec 15. Mol Cell Biol. 2015. PMID: 25512612 Free PMC article.

2

Zebrafish models of leukemia.

He S, Jing CB, Look AT. He S, et al. Methods Cell Biol. 2017;138:563-592. doi: 10.1016/bs.mcb.2016.11.013. Epub 2017 Jan 7. Methods Cell Biol. 2017. PMID: 28129858 Review.

3

Malignant Peripheral Nerve Sheath Tumors.

Durbin AD, Ki DH, He S, Look AT. Durbin AD, et al. Among authors: he s. Adv Exp Med Biol. 2016;916:495-530. doi: 10.1007/978-3-319-30654-4_22. Adv Exp Med Biol. 2016. PMID: 27165368 Review.

4

Synthetic lethal targeting of TET2-mutant hematopoietic stem and progenitor cells (HSPCs) with TOP1-targeted drugs and PARP1 inhibitors.

Jing CB, Fu C, Prutsch N, Wang M, He S, Look AT. Jing CB, et al. Among authors: he s. Leukemia. 2020 Nov;34(11):2992-3006. doi: 10.1038/s41375-020-0927-5. Epub 2020 Jun 22. Leukemia. 2020. PMID: 32572188

5

Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors.

Ki DH, He S, Rodig S, Look AT. Ki DH, et al. Among authors: he s. Oncogene. 2017 Feb 23;36(8):1058-1068. doi: 10.1038/onc.2016.269. Epub 2016 Aug 1. Oncogene. 2017. PMID: 27477693 Free PMC article.

6

Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain.

He S, Mansour MR, Zimmerman MW, Ki DH, Layden HM, Akahane K, Gjini E, de Groh ED, Perez-Atayde AR, Zhu S, Epstein JA, Look AT. He S, et al. Elife. 2016 Apr 27;5:e14713. doi: 10.7554/eLife.14713. Elife. 2016. PMID: 27130733 Free PMC article.

7

JDP2: An oncogenic bZIP transcription factor in T cell acute lymphoblastic leukemia.

Mansour MR, He S, Li Z, Lobbardi R, Abraham BJ, Hug C, Rahman S, Leon TE, Kuang YY, Zimmerman MW, Blonquist T, Gjini E, Gutierrez A, Tang Q, Garcia-Perez L, Pike-Overzet K, Anders L, Berezovskaya A, Zhou Y, Zon LI, Neuberg D, Fielding AK, Staal FJT, Langenau DM, Sanda T, Young RA, Look AT. Mansour MR, et al. Among authors: he s. J Exp Med. 2018 Jul 2;215(7):1929-1945. doi: 10.1084/jem.20170484. Epub 2018 Jun 25. J Exp Med. 2018. PMID: 29941549 Free PMC article.

8

The MCL1-specific inhibitor S63845 acts synergistically with venetoclax/ABT-199 to induce apoptosis in T-cell acute lymphoblastic leukemia cells.

Li Z, He S, Look AT. Li Z, et al. Among authors: he s. Leukemia. 2019 Jan;33(1):262-266. doi: 10.1038/s41375-018-0201-2. Epub 2018 Jul 15. Leukemia. 2019. PMID: 30008477 Free PMC article. No abstract available.

9

Synergistic melanoma cell death mediated by inhibition of both MCL1 and BCL2 in high-risk tumors driven by NF1/PTEN loss.

He S, Zimmerman MW, Layden HM, Berezovskaya A, Etchin J, Martel MW, Thurston G, Jing CB, van Rooijen E, Kaufman CK, Rodig SJ, Zon LI, Patton EE, Mansour MR, Look AT. He S, et al. Oncogene. 2021 Sep;40(38):5718-5729. doi: 10.1038/s41388-021-01926-y. Epub 2021 Jul 30. Oncogene. 2021. PMID: 34331013 Free PMC article.

10

suz12 inactivation in p53- and nf1-deficient zebrafish accelerates the onset of malignant peripheral nerve sheath tumors and expands the spectrum of tumor types.

Oppel F, Ki DH, Zimmerman MW, Ross KN, Tao T, Shi H, He S, Aster JC, Look AT. Oppel F, et al. Among authors: he s. Dis Model Mech. 2020 Aug 27;13(8):dmm042341. doi: 10.1242/dmm.042341. Dis Model Mech. 2020. PMID: 32651197 Free PMC article.

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