Yin J - Search Results

1

Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant.

Yin J, Mobarec JC, Kolb P, Rosenbaum DM. Yin J, et al. Nature. 2015 Mar 12;519(7542):247-50. doi: 10.1038/nature14035. Epub 2014 Dec 22. Nature. 2015. PMID: 25533960

2

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors.

Yin J, Babaoglu K, Brautigam CA, Clark L, Shao Z, Scheuermann TH, Harrell CM, Gotter AL, Roecker AJ, Winrow CJ, Renger JJ, Coleman PJ, Rosenbaum DM. Yin J, et al. Nat Struct Mol Biol. 2016 Apr;23(4):293-9. doi: 10.1038/nsmb.3183. Epub 2016 Mar 7. Nat Struct Mol Biol. 2016. PMID: 26950369

3

High-resolution crystal structure of the human CB1 cannabinoid receptor.

Shao Z, Yin J, Chapman K, Grzemska M, Clark L, Wang J, Rosenbaum DM. Shao Z, et al. Among authors: yin j. Nature. 2016 Dec 22;540(7634):602-606. doi: 10.1038/nature20613. Epub 2016 Nov 16. Nature. 2016. PMID: 27851727 Free PMC article.

4

The Human Orexin/Hypocretin Receptor Crystal Structures.

Yin J, Rosenbaum DM. Yin J, et al. Curr Top Behav Neurosci. 2017;33:1-15. doi: 10.1007/7854_2016_52. Curr Top Behav Neurosci. 2017. PMID: 28025809 Review.

5

Crystal structure of the human NK₁ tachykinin receptor.

Yin J, Chapman K, Clark LD, Shao Z, Borek D, Xu Q, Wang J, Rosenbaum DM. Yin J, et al. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):13264-13269. doi: 10.1073/pnas.1812717115. Epub 2018 Dec 11. Proc Natl Acad Sci U S A. 2018. PMID: 30538204 Free PMC article.

6

An improved yeast surface display platform for the screening of nanobody immune libraries.

Uchański T, Zögg T, Yin J, Yuan D, Wohlkönig A, Fischer B, Rosenbaum DM, Kobilka BK, Pardon E, Steyaert J. Uchański T, et al. Among authors: yin j. Sci Rep. 2019 Jan 23;9(1):382. doi: 10.1038/s41598-018-37212-3. Sci Rep. 2019. PMID: 30674983 Free PMC article.

7

Structure of an allosteric modulator bound to the CB1 cannabinoid receptor.

Shao Z, Yan W, Chapman K, Ramesh K, Ferrell AJ, Yin J, Wang X, Xu Q, Rosenbaum DM. Shao Z, et al. Among authors: yin j. Nat Chem Biol. 2019 Dec;15(12):1199-1205. doi: 10.1038/s41589-019-0387-2. Epub 2019 Oct 28. Nat Chem Biol. 2019. PMID: 31659318

8

Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane.

Yin J, Chen KM, Clark MJ, Hijazi M, Kumari P, Bai XC, Sunahara RK, Barth P, Rosenbaum DM. Yin J, et al. Nature. 2020 Aug;584(7819):125-129. doi: 10.1038/s41586-020-2379-5. Epub 2020 Jun 11. Nature. 2020. PMID: 32528175 Free PMC article.

9

Structure-based development of a subtype-selective orexin 1 receptor antagonist.

Hellmann J, Drabek M, Yin J, Gunera J, Pröll T, Kraus F, Langmead CJ, Hübner H, Weikert D, Kolb P, Rosenbaum DM, Gmeiner P. Hellmann J, et al. Among authors: yin j. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18059-18067. doi: 10.1073/pnas.2002704117. Epub 2020 Jul 15. Proc Natl Acad Sci U S A. 2020. PMID: 32669442 Free PMC article.

10

Molecular mechanism of the wake-promoting agent TAK-925.

Yin J, Kang Y, McGrath AP, Chapman K, Sjodt M, Kimura E, Okabe A, Koike T, Miyanohana Y, Shimizu Y, Rallabandi R, Lian P, Bai X, Flinspach M, De Brabander JK, Rosenbaum DM. Yin J, et al. Nat Commun. 2022 May 25;13(1):2902. doi: 10.1038/s41467-022-30601-3. Nat Commun. 2022. PMID: 35614071 Free PMC article.

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