Moore Z - Search Results

1

NAMPT inhibition sensitizes pancreatic adenocarcinoma cells to tumor-selective, PAR-independent metabolic catastrophe and cell death induced by β-lapachone.

Moore Z, Chakrabarti G, Luo X, Ali A, Hu Z, Fattah FJ, Vemireddy R, DeBerardinis RJ, Brekken RA, Boothman DA. Moore Z, et al. Cell Death Dis. 2015 Jan 15;6(1):e1599. doi: 10.1038/cddis.2014.564. Cell Death Dis. 2015. PMID: 25590809 Free PMC article.

2

Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone.

Chakrabarti G, Moore ZR, Luo X, Ilcheva M, Ali A, Padanad M, Zhou Y, Xie Y, Burma S, Scaglioni PP, Cantley LC, DeBerardinis RJ, Kimmelman AC, Lyssiotis CA, Boothman DA. Chakrabarti G, et al. Cancer Metab. 2015 Oct 12;3:12. doi: 10.1186/s40170-015-0137-1. eCollection 2015. Cancer Metab. 2015. PMID: 26462257 Free PMC article.

3

Tumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.

Chakrabarti G, Silvers MA, Ilcheva M, Liu Y, Moore ZR, Luo X, Gao J, Anderson G, Liu L, Sarode V, Gerber DE, Burma S, DeBerardinis RJ, Gerson SL, Boothman DA. Chakrabarti G, et al. Sci Rep. 2015 Nov 25;5:17066. doi: 10.1038/srep17066. Sci Rep. 2015. PMID: 26602448 Free PMC article.

4

Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors.

Huang X, Motea EA, Moore ZR, Yao J, Dong Y, Chakrabarti G, Kilgore JA, Silvers MA, Patidar PL, Cholka A, Fattah F, Cha Y, Anderson GG, Kusko R, Peyton M, Yan J, Xie XJ, Sarode V, Williams NS, Minna JD, Beg M, Gerber DE, Bey EA, Boothman DA. Huang X, et al. Cancer Cell. 2016 Dec 12;30(6):940-952. doi: 10.1016/j.ccell.2016.11.006. Cancer Cell. 2016. PMID: 27960087 Free PMC article.

5

Nanotechnology-enabled delivery of NQO1 bioactivatable drugs.

Ma X, Moore ZR, Huang G, Huang X, Boothman DA, Gao J. Ma X, et al. J Drug Target. 2015;23(7-8):672-80. doi: 10.3109/1061186X.2015.1073296. J Drug Target. 2015. PMID: 26453163 Review.

6

Fibulin-5 Blocks Microenvironmental ROS in Pancreatic Cancer.

Wang M, Topalovski M, Toombs JE, Wright CM, Moore ZR, Boothman DA, Yanagisawa H, Wang H, Witkiewicz A, Castrillon DH, Brekken RA. Wang M, et al. Cancer Res. 2015 Dec 1;75(23):5058-69. doi: 10.1158/0008-5472.CAN-15-0744. Epub 2015 Nov 17. Cancer Res. 2015. PMID: 26577699 Free PMC article.

7

Superparamagnetic iron oxide nanoparticles: amplifying ROS stress to improve anticancer drug efficacy.

Huang G, Chen H, Dong Y, Luo X, Yu H, Moore Z, Bey EA, Boothman DA, Gao J. Huang G, et al. Among authors: moore z. Theranostics. 2013;3(2):116-26. doi: 10.7150/thno.5411. Epub 2013 Feb 1. Theranostics. 2013. PMID: 23423156 Free PMC article.

8

Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy.

Ma X, Huang X, Moore Z, Huang G, Kilgore JA, Wang Y, Hammer S, Williams NS, Boothman DA, Gao J. Ma X, et al. Among authors: moore z. J Control Release. 2015 Feb 28;200:201-11. doi: 10.1016/j.jconrel.2014.12.027. Epub 2014 Dec 24. J Control Release. 2015. PMID: 25542645 Free PMC article.

9

Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers.

Cao L, Li LS, Spruell C, Xiao L, Chakrabarti G, Bey EA, Reinicke KE, Srougi MC, Moore Z, Dong Y, Vo P, Kabbani W, Yang CR, Wang X, Fattah F, Morales JC, Motea EA, Bornmann WG, Yordy JS, Boothman DA. Cao L, et al. Among authors: moore z. Antioxid Redox Signal. 2014 Jul 10;21(2):237-50. doi: 10.1089/ars.2013.5462. Epub 2014 Apr 3. Antioxid Redox Signal. 2014. PMID: 24512128 Free PMC article.

10

Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers.

Bey EA, Reinicke KE, Srougi MC, Varnes M, Anderson VE, Pink JJ, Li LS, Patel M, Cao L, Moore Z, Rommel A, Boatman M, Lewis C, Euhus DM, Bornmann WG, Buchsbaum DJ, Spitz DR, Gao J, Boothman DA. Bey EA, et al. Among authors: moore z. Mol Cancer Ther. 2013 Oct;12(10):2110-20. doi: 10.1158/1535-7163.MCT-12-0962. Epub 2013 Jul 24. Mol Cancer Ther. 2013. PMID: 23883585 Free PMC article.

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