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Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion.
Yaghootkar H, Stancáková A, Freathy RM, Vangipurapu J, Weedon MN, Xie W, Wood AR, Ferrannini E, Mari A, Ring SM, Lawlor DA, Davey Smith G, Jørgensen T, Hansen T, Pedersen O, Steinthorsdottir V, Guðbjartsson DF, Thorleifsson G, Thorsteinsdottir U, Stefansson K, Hattersley AT, Walker M, Morris AD, McCarthy MI, Palmer CN, Laakso M, Frayling TM. Yaghootkar H, et al. Among authors: davey smith g. Diabetes. 2015 Jun;64(6):2279-85. doi: 10.2337/db14-1456. Epub 2015 Jan 20. Diabetes. 2015. PMID: 25605810 Free PMC article.
1,177 results