Kuwano M - Search Results

1

CpG hypermethylation contributes to decreased expression of PTEN during acquired resistance to gefitinib in human lung cancer cell lines.

Maeda M, Murakami Y, Watari K, Kuwano M, Izumi H, Ono M. Maeda M, et al. Among authors: kuwano m. Lung Cancer. 2015 Mar;87(3):265-71. doi: 10.1016/j.lungcan.2015.01.009. Epub 2015 Jan 20. Lung Cancer. 2015. PMID: 25638724

2

Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs.

Ono M, Kuwano M. Ono M, et al. Among authors: kuwano m. Clin Cancer Res. 2006 Dec 15;12(24):7242-51. doi: 10.1158/1078-0432.CCR-06-0646. Clin Cancer Res. 2006. PMID: 17189395 Review.

3

N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor of kappaB kinase beta expression.

Hosoi F, Izumi H, Kawahara A, Murakami Y, Kinoshita H, Kage M, Nishio K, Kohno K, Kuwano M, Ono M. Hosoi F, et al. Among authors: kuwano m. Cancer Res. 2009 Jun 15;69(12):4983-91. doi: 10.1158/0008-5472.CAN-08-4882. Epub 2009 Jun 2. Cancer Res. 2009. PMID: 19491262

4

Loss of PTEN expression by blocking nuclear translocation of EGR1 in gefitinib-resistant lung cancer cells harboring epidermal growth factor receptor-activating mutations.

Yamamoto C, Basaki Y, Kawahara A, Nakashima K, Kage M, Izumi H, Kohno K, Uramoto H, Yasumoto K, Kuwano M, Ono M. Yamamoto C, et al. Among authors: kuwano m. Cancer Res. 2010 Nov 1;70(21):8715-25. doi: 10.1158/0008-5472.CAN-10-0043. Epub 2010 Oct 19. Cancer Res. 2010. PMID: 20959484

5

Expression of selected gene for acquired drug resistance to EGFR-TKI in lung adenocarcinoma.

Uramoto H, Shimokawa H, Hanagiri T, Kuwano M, Ono M. Uramoto H, et al. Among authors: kuwano m. Lung Cancer. 2011 Sep;73(3):361-5. doi: 10.1016/j.lungcan.2011.01.008. Epub 2011 Feb 18. Lung Cancer. 2011. PMID: 21315472

6

Loss of activating EGFR mutant gene contributes to acquired resistance to EGFR tyrosine kinase inhibitors in lung cancer cells.

Tabara K, Kanda R, Sonoda K, Kubo T, Murakami Y, Kawahara A, Azuma K, Abe H, Kage M, Yoshinaga A, Tahira T, Hayashi K, Arao T, Nishio K, Rosell R, Kuwano M, Ono M. Tabara K, et al. Among authors: kuwano m. PLoS One. 2012;7(7):e41017. doi: 10.1371/journal.pone.0041017. Epub 2012 Jul 17. PLoS One. 2012. PMID: 22815900 Free PMC article.

7

Y-box binding protein-1 contributes to both HER2/ErbB2 expression and lapatinib sensitivity in human gastric cancer cells.

Shibata T, Kan H, Murakami Y, Ureshino H, Watari K, Kawahara A, Kage M, Hattori S, Ono M, Kuwano M. Shibata T, et al. Among authors: kuwano m. Mol Cancer Ther. 2013 May;12(5):737-46. doi: 10.1158/1535-7163.MCT-12-1125. Epub 2013 Feb 27. Mol Cancer Ther. 2013. PMID: 23445612

8

Erlotinib resistance in lung cancer cells mediated by integrin β1/Src/Akt-driven bypass signaling.

Kanda R, Kawahara A, Watari K, Murakami Y, Sonoda K, Maeda M, Fujita H, Kage M, Uramoto H, Costa C, Kuwano M, Ono M. Kanda R, et al. Among authors: kuwano m. Cancer Res. 2013 Oct 15;73(20):6243-53. doi: 10.1158/0008-5472.CAN-12-4502. Epub 2013 Jul 19. Cancer Res. 2013. PMID: 23872583

9

FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib, a pan-EGFR family kinase inhibitor.

Azuma K, Kawahara A, Sonoda K, Nakashima K, Tashiro K, Watari K, Izumi H, Kage M, Kuwano M, Ono M, Hoshino T. Azuma K, et al. Among authors: kuwano m. Oncotarget. 2014 Aug 15;5(15):5908-19. doi: 10.18632/oncotarget.1866. Oncotarget. 2014. PMID: 25115383 Free PMC article.

10

Overcoming drug resistance to receptor tyrosine kinase inhibitors: Learning from lung cancer.

Kuwano M, Sonoda K, Murakami Y, Watari K, Ono M. Kuwano M, et al. Pharmacol Ther. 2016 May;161:97-110. doi: 10.1016/j.pharmthera.2016.03.002. Epub 2016 Mar 18. Pharmacol Ther. 2016. PMID: 27000770 Review.

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